"Ritmonorm": analogue, ixabiso, nemiyalelo yokusebenzisa

"Ritmonorm" - ichiza amanyathelo antiarrhythmic. Xa usebenzisa iibhloko beziyobisi channels sodium. Eli chiza a ngqo inyathelo inwebu-ozinzileyo kuchaphazela myocardiocytes. Phambi iipropati ukufunda unyango "Ritmonorm" iziyobisi, imiyalelo ukusetyenziswa, kunoogxa yokwenene. Phawula olu lwazi ngokweenkcukacha.

components iziyobisi, Composition

Amalungiselelo yenziwe ngohlobo iipilisi camera. I esebenzayo into isetyenziswa kuhlanganiselo - hydrochloride propafenone. tablet nganye 150 mg esisebenza. Tablets ziqulathe okunye ezifana titanium dioxide, microcrystalline kwincindi, starch asuka umbona starch nemagnesium stearate, hydroxypropylmethylcellulose 2910 kunye sodium croscarmellose. Phakathi kwezinye amacandelo ozikhethelayo - macrogol 6000 kwaye macrogol 400, amanzi okuhlamba.

ukusebenza beziyobisi

Kunciphisa kwesona santya siphezulu kunokwenzeka, nto leyo kwenzeka kunye depolarization elo amandla (isigaba 0), kanye ziyobisi kuchaphazela awo le imicu (iinkxalabo zombini imicu contractile ventricular kunye Purkinje) abangaphangeliyo ukuphunyezwa oluzenzekelayo. Oqhuba imicu Purkinje elicothayo, ixesha apho lokuqhutywa, nto leyo yaqaphela imithambo kunye esiludumbo sinoatrial, sandisiwe. "Ritmonorm" analogue iziyobisi kuba nafuthe ezichanekileyo ixesha elifunekayo ukuze kuqheleke umsebenzi yababephethwe esiludumbo sinus ngexesha yashukunyiswa umbane, nokuba isiphumo esifanayo engephi. imiphumela Electrophysiological ziyabonakala ischemia engcono engabalulekanga, ifuthe m-holino- beta-adrenoceptor ekuvimbeni mnene.

Le medicament "Ritmonorm" analogue iziyobisi na izinto zabo ekwakhiweni ezinika inkonzo inyathelo negative inotropic, nto leyo edla ekhoyo xa isalathisi se ventricular lasekhohlo ejection iqhezu lifinyele.

Umsebenzi lo medicament luchazwa iintlungu wengingqi, kukho ukufana ne umsebenzi "Procaine". Qhubeka "Ritmonorm" iqala engama-60 emva kokuba ukusetyenziswa lwangaphakathi. Ukusebenza liphezulu ichiza Sithole emva umlinganiselo weeyure 2.5 emva kokungena umzimba, ubude isiphumo efunyenweyo egcinwa ukuba umlinganiselo weeyure ezili-10.

Xa ukufakwa yokwamkela yangaphakathi kwi phecana zesisu lwenzeka phantse yonke. Yokucolwa esibindini. Ichiza siboniswe ngokuyinxenye iiyure ezi-5 kwaye lisuswe emzimbeni njengoko metabolites kwi nezintso nomhlehlo wesibindi, ekhona enyongweni.

ubungqina

"Ritmonorm" arhente analogs elawulwa ukunyanga esi sifo. Iipilisi asetyenziswa kwezi meko zilandelayo:

• fibrillation ventricular;
• tachyarrhythmia paroxysmal supraventricular.

Izimo

Izimo zezi zilandelayo:

• Hypersensitivity ukuba amacandelo ichiza;
• bradycardia wabonisa;
• syndrome apho ephawulwe sinus;
• nesifo sentliziyo imvelo ezingapheliyo;
• myasthenia gravis;
• ukuncipha ko- wegazi;
• bronchospasm;
• ixesha lokumitha umntwana, emondla ubisi lwebele;
• isifo obstructive apho emiphungeni achaphazeleka ziyenzeka enzima onesifo;
• WaBantwana yobudala (abaneminyaka engaphantsi kwe-18);
• wavakalisa iingxaki intraventricular, atrioventricular kunye Uhanjiso sinoatrial;
• nezitenxo awasiwisayo izintso wesibindi;
• mothuko cardiogenic ngaphandle athuke arrhythmic;
• hyper- okanye hypokalemia.

"Ritmonorm" analogue iziyobisi azivunyelwa ukuba zisebenzise le kwiinyanga ezintathu zokuqala, ukuba umntu wahlaselwa yintliziyo okanye ukwehla ventricular lasekhohlo ejection amaqhekeza. Ezi nketho zizigulane abaqatshelwe ventricular fibrillation, imeko leyo okubeka impilo nje kuphela, kodwa ubomi.

Ezinye iimeko abafuna inkathalo ngethuba unyango kufuna kweliso unyango ngenyameko.

ukusetyenziswa kweziyobisi

Iipilisi asele emva ukudla, ukuginya yonke. Ubude unyango lusekiwe igqirha kuthathelwa ingqalelo izinto ezininzi. Kukwasebenza kwanjalo kuyo iidosi lithetha "Ritmonorm". Analogs of malungiselelo ixabiso (ngaphantsi) wenza iindlela abahlelelekileyo azibi. La machiza nazo wenze kakuhle lo msebenzi, kodwa isiphumo yabo yahluke kancinane.

Ngelo isanda kucetyiswa ukuba ziphathwe esibhedlele. izigulane abadala enobunzima ngaphezulu kwama-70 kg emiselweyo unyango, ngokusekelwe yokwamkelwa ukulungiselela ngokuphindwe kathathu. Ngokuqhelekileyo, ithamo ukuba zityiwe ngexesha elinye ngu 150 mg.

Kwiimeko apho lokuphumla QT kunye QRS ezintsonkothileyo landa nge-20% okanye ngaphezulu xa kuthelekiswa nezo eziye babeke phambi kokuqalisa unyango, ithamo lifinyele. Kukho enye indlela - into ukupheliswa unyango okwethutyana.

amathamo aphezulu ichiza ingaqhuba iye phandle, ukugcina isithuba iintsuku ezintathu. Kulo mzekelo, kunokwenzeka ukuba ukwandisa ukuya kutsho kuma-mg 300 kabini ngosuku (ngamanye amaxesha amathathu).

Izigulane ebudaleni ezinobunzima umzimba elingagqithanga 70 kg banikwa ngeedosi nokuphungulwa of "Ritmonorm" (amacwecwe) beziyobisi. Ukuphononongwa, iinkcazelo, izixhobo analogue kukuvumela ukuba ukuvavanya amathuba amayeza kwaye endaweni yayo, xa kuyimfuneko.

Xa ichiza baphathwa izigulane ezineengxaki wesibindi, ithamo esetyenzisiweyo, kuncitshiswa yi-20-30% (njengoko cumulation kuyenzeka) kunye iingxaki zezintso - kungancitshiswa ngama- 50%.

imiphumela emibi

Utshintsho nomonde olunzulu iinkqubo sentliziyo luvo, iphecana zesisu nga andibhaqwa. ukunyhashwa kunokwenzeka kwenkqubo ekuzaleni kunye utshintsho parameters elebhu. Phakathi kwezinye ziziphumo ebezingalindelekanga - irhashalala kwesikhumba (ukopha), arthralgia. Bronchospasm Inokwenzeka, ubuthathaka jikelele.

oyi

lolwamkelo esikolweni "Ritmonorm" kuthetha ukuba uyeke xa kuyimfuneko. Analogs nawethutyana, ichiza kufuneka licwangciswe ngugqirha wakho. Rhoxisa "Ritmonorma" kunokwenzeka emva kokufumana iingcebiso specialist.

Unyango kudinga uhlolo rhoqo yohlengahlengiso electrolytes kunye ECGs. Ngamaxesha athile, kuyimfuneko ukulawula kunye neminye imiqondiso leyo.

Xa ukuphatha izigulane abazibandakanyileyo ipacemaker esifakelweyo, kufuneka sinikele ingqalelo iinguqu ehambahamba umbundu defibrillation. indyebo yawo yenza umyalelo iparameters ulungiso usebenza-ntliziyo.

Ichiza mazithathwe ngokuqaphela kwabo aqhube isithuthi okanye inxaxheba kwizinto ezifuna impendulo ekhawulezileyo kunye nokhathalelo.

Abo uceba ukuphathwa "Ritmonorm" uthetha umyalelo, ixabiso ezikhemisti analogue kusenokuba umdla. Apha ngezantsi kukho iindleko ichiza njengamalalela angqina abantu abaye baphathwa "Ritmonormom" yaye kwabelwane ngezimvo zabo.

Analogs, iindleko ichiza, izigxeko

Price of ichiza malunga 545-700 engange. ngokuba diphu iipilisi (50 iiPC.). Phakathi analogue aziwayo - "Profenan", "Propastad", "Prolekofen". Kudla amagqirha ukumisela endaweni "Propafenone RP 300" okanye uvelisa "propafenone RP 150" replacement iziyobisi. Ukuba ufuna ukukhetha analog anganika kuqala ku "propafenone" okanye "propanorm".

Ngaphambi kokuba unyango, amayeza "Ritmonorm" analogue, ixabiso, imiyalelo zokusetyenziswa ayikho into kuphela ukuhlola. Kuluncedo ukuba simazi. Njengoko ukubuyekeza, ichiza ukuba umntu onokunceda, yaye umntu akazange enze naliphi na isiphumo. Kukho abantu uthathe amayeza xa uziva mnandi, kukho kwakhona nabo ababehlekisa ngabo phezu ngengcebiso kagqirha. Ukuba isiphumo kulindeleke ayifumaneki, kukho imfuneko ukuze zihlolwe eyongezelelweyo ukuze kulungiswe ezi rejimeni lusekiwe unyango.