Phosphatase awana - enzyme ebalulekileyo umzimba womntu

Ukuza kuthi ga ngoku, uxilongo oluntsonkothileyo izifo ezininzi kusetyenziswa iindlela kwilebhu iimviwo. Oku kuquka uhlalutyo zengqo- igazi.

phosphatase awana: iimpawu jikelele enzyme

phosphatase awana - ngenye ibalulekileyo. Le ephindeneyo enzayimi leyo ebonisa umsebenzi phosphatase. Kuyinto khona phantse zonke iiseli zabantu. umsebenzi wayo eliphezulu kuboniswa ngendlela obrak eliphakathi kwaye ezinxulumene ingaphandle iseli. Ukufumaneka eliphezulu le compound kubhalwa osteoblasts (iiseli in esiqwini amathambo), iiseli isibindi kunye tubules sezintso kwi isifo isisu, kwakunye ngumkhaya. phosphatase awana, nto leyo siqulethwe kwi-serum, njengoko umthetho, livela ithambo okanye hepatocytes. umsebenzi yalo phezulu liyasetyenziswa kakhulu izifo zesibindi ezithi zenzeke kunye nezithintelo ye bile duct, ngokunjalo izitshanguba ngethambo zikhatshwa nqubo amathambo.

inqanaba phosphatase awana iphezulu. Kutheni?

Zininzi ithi sifo banda apho phosphatase obrak. Ummiselo zesi salathisi ixhomekeke yobudala kunye ngesondo, ngoko zikuthathele ingqalelo oku xa etolika ngamachiza igazi.

Phakathi imiba etiological ezinokuchaphazela kwinqanaba enqanda, kuquka phosphatase obrak, ifanele ukubandakanya oku kulandelayo:

• ukukhulelwa;

• Postmenopausal;

• inani elingonelanga calcium ukungondleki, phosphate;

• ezingaphezu ascorbic acid emzimbeni;

• ukusetyenziswa arhente amayeza esinye (umz, zokucwangcisa eziqulathe estrogen kunye dlala, kwakunye antibiotics).

Ukongeza, ialakalin phosphatase kufuneka zandiswe ezi zifo zilandelayo:

• hyperparathyroidism;

• isifo sentliziyo kwezintso okanye inyama lung;

• ezigula multiple;

• mononucleosis esosulelayo;

• Isifo bone, kuquka umhlaza yobomi;

• Isifo Hodgkin, nto leyo eyenzeka ngokutshatyalaliswa amathambo;

• yamathambo;

• sisilonda esidumbileyoesingaphakathi ebulalayo Kwiphecana biliary;

• ukudumba uhlobo ezosulelayo okanye ukuqina kwesibindi, isifo sephepha yayo amoyise.

Umyalezo weimeyile ukunciphisa phosphatase obrak

Kukho eziliqela ezimbi apho, phezu koko, phosphatase obrak lifinyele. Ngenxa yoko, izinga enzyme ngezantsi eqhelekileyo hypothyroidism. Ukophulwa wokukhula ithambo, ukuswela nezinki, kwakunye kwegazi - izinto etiological ezinokuchaphazela imali phosphatase obrak kwi serum egazini. Ukuthatha amayeza athile kwakhona ukutshintsha iziphumo zovavanyo. Ukongezelela, ubukho nangokhwekhwe, leyo iphuhlise ngenxa insufficiency of ascorbic acid kukhokelela ekuncipheni kwe-enzyme.

Kufuneka kuqatshelwe ukuba ukhulelwe phosphatase obrak nga ukukhula ngokwandisa inani isoenzyme placental. Oku Zinjalo izigaba zokugqibela zokumitha kwaye ezinxulumene kunye nophuhliso ubuninzi ngumkhaya. Loo ipateni akukho ixabiso diagnostic, ngoko ke akukho Akusebenzi yokuvavanywa urhulumente umama okanye usana olungekazalwa. Kwiimeko xa owasetyhini ene insufficiency placental, uyazikhomba le compound lifinyele enzyme.

Iimpawu shintsho inqanaba phosphatase obrak

phosphatase awana na ngohlobo isoenzymes eziliqela. Ubungakanani sokukhula xi lo ephindeneyo ngamazinga kunye osteoblastic esebenzayo (ithambo inkqubo ukwakhiwa), ukwenzela ukuba zinga liphezulu isoenzyme bone waphawula izifo Paget kaThixo. Ukuba isigulane kuphuhlisa ngezifo umsebenzi osteolytic (umzekelo, ezigula ezininzi), ukunyuka phosphatase obrak, kodwa kancinane kuphela.

Xa izitshanguba kwenkqubo hepatobiliary kwandisa hepatic isoenzyme. Xa kusenziwa lwezonyango, lisetyenziswa njengendlela isiphawuli of cholestasis. Kulo mzekelo, ukulahlekelwa ngqo weeseli zesibindi kungathatha indawo ngokuchasene nentsukaphi amanqanaba eziqhelekileyo okanye asezantsi phosphatase obrak. Le ndlela ekuso, njengoko umthetho, kuninzi amatyala lwezonyango, nangona ukuze waphawula isigulane ngamnye, nkqu umonakalo esibindini okanye iphecana biliary.

Kubalulekile ukuphawula ukuba ukwanda phosphatase obrak emntwaneni - into komzimba, nto leyo ehambisana kunye nokukhula kakhulu. Ngenxa yoko, izinga le enzyme abantwana bafikelele kwinqanaba amakhulu eqhelekileyo ukuba umntu omdala amaxesha 1.5-2 (ukusuka 82 ukuya 341 U / L).

Okukodwa ukulinganisa izinga phosphatase obrak

Ukuza kuthi ga ngoku, iimeko kangangoko ukwenzela uhlalutyo nengqwalaselo kwizithuba uyondelelwano lwee- phosphatase obrak yahlukile, kuba Ilabhoratri nganye imilinganiselo yayo. Kukho iindlela kulingwa eziliqela leyo ixhomekeke zeendawana enzyme kunye nenkqubo lwezimali kwakunye lobushushu apho ziyabanjwa zeesampulu. imida Uniform isibonisi "ialakalin phosphatase" akakho, ngoko ke akukho mfuneko ukuthelekisa amaxabiso enzyme, ezo zifunyenwe bokuba ezahlukeneyo. Oku kuyinyaniso ngakumbi xa akwaziwa into olawula ezi iilabhoratri ebekwe.

Localulo serum igazi iyasetyenziswa. Kwiimeko ezininzi, ngokuthatha umaleko phezulu, oluthi luqokelelane umahluli ityhubhu. Kubalulekile ukuqaphela ukuba izinga phosphatase obrak ukuba ngempazamo wande, ukuba tourniquet isampuli yegazi phezu kwesebe eliphezulu siwisiwe imizuzwana engaphezu kwama-30. Ukongeza, umsebenzi lo enzyme zisenokwahluka kancinane ukuba isampuli igazi mazilondolozwe kubushushu igumbi. Kule hemolysis in vitro aluchaphazeli iziphumo zovavanyo.

Kufuneka wenze ntoni xa inqanaba zophendlo lwezifo ze phosphatase obrak?

Xa awana phosphatase landa, unyango kufuneka abe etiological. Ngaloo ndlela, ubukho isibindi okanye biliary izifo kufuneka ukuba bajonge gastroenterologist. Cholestasis, phambi pancreatitis, ukuqina okanye ukuqina kufuna ahambelanayo ulungiso ichiza kabani lesixa kumiselwa kuphela ngugqirha. Self kulo mzekelo kungakhokelela ekubeni ukuqhubela phambili kwesifo zaseprayimari.

Ukutshintsha ingqondo enqanda, kuquka phosphatase obrak, kufuneka iqatshelwe ukusilela sentliziyo, umhlaza ngezifo kunye umonakalo omkhulu nezintso, kwakunye nesifo seswekile, ngoko ke kufuneka ukuba bajonge cardiologist, nephrologist okanye endocrinologist. Ugqirha uya kumisela amaqhinga zonyango ngokuxhomekeke umfanekiso lwezonyango.

Ekumfuduseni imiba etiological, umsebenzi phosphatase obrak ubuyela eqhelekileyo. Ekuqeshweni unyango kufuneka ithathelwe ingqalelo into yokuba, umzekelo, ukwanda komzimba zesi salathisi kunokwenzeka kunye kwizaphuko, ukukhula esebenzayo kwenkqubo skeletal, kunye yokumitha. It ayifuni ungenelelo lonyango. Ukutolikwa iziphumo zeemvavanyo elabhoratri kwenziwa ngokubanzi, kuthathelwe ingqalelo ezinye kwemichiza iparameters kunye nezikhalazo nomonde.