Mefenamic acid

"Mefenamic acid" - ichiza esisetyenziswa ngokubanzi kwi arthrology, unyango lwezifo ezosulelayo ekumila kwiintetho ezikralayo, iimpawu kobuchopho.

Eli chiza fanele ukuba iqela amayeza izinto fenamates - izinto ukuba isiphumo anti-ukudumba. "Mefenamic acid 'uye ngokwalo njengento antipyretic obalaseleyo kunye iintlungu.

Eli chiza ngeendlela entsonkothileyo amanyathelo kubandakanya inxaxheba ngqo kwi abasabela arhabaxa. "Mefenamic acid" (into esebenzayo) kuphungula kuyondelelaniswe kwezinto ezithile (mediators), ezibandakanya prostaglandins, kinin, serotonin. Ngaphezu koko, ngokubonakalayo kunciphisa umsebenzi kwi-enzayim lysosomal proteolytic, inxaxheba ngqo kwizigaba zokuqala ezimbini ukudumba: exudation, ukwanda. Okunye Iziphumo kweli chiza ziquka: nokuzinzisa of inwebu yeseli kunye ultrastructures protein, ukunciphisa permeability nemithambo kunye ukudumba izicwili abachaphazelekayo, ukwandisa umsebenzi serotonin, ukwanda ukungawi kwiiseli, ukukhuthazwa kweenkqubo kutsha. effect isiyobisi iintlungu ke ifuthe ngqo kwi indlela umbindi nobuzaza iintlungu, ngokunjalo Namanyathelo athathwa kwingingqi kuxhomekeka kugqaliso arhabaxa. Iipropati Antipyretic sizibandakanya ngqo ethintela prostaglandin yokuqaphela, iziphumo kwiziko thermoregulatory apha ebuchotsheni. Enye feature ukukhuthaza imveliso interferon, nto leyo iphucula ngqo iimpawu proliferative ukwimo esebenzayo.

Mefenamic acid onokufunxa sezingeni eliphezulu. Le xi eliphezulu ifunyanwa emva kweeyure ezimbini ukuya kwezine emva kokuba ulwamkelo. Izinga kweziyobisi igazi umlinganiselo ukuba ngaso yedosi yayo ifunyenwe. WezoThutho yegazi beziyobisi lwenzeka ngokuzibophelela kwi albumin. Kwisiqingatha ubomi ukwimo esebenzayo ziiyure ezintathu. Malunga amathandathu ekhulwini esiswini saso umchamo ekwimo phantse kutshintsha, amashumi amabini anesihlanu - kunye endleni.

"Mefenamic acid 'uye emininzi ebanzi ngokwaneleyo umsebenzi, nto leyo ungachazwa nobuninzi yeziphumo eyenza arhente esebenzayo. izifo kunye nezimpawu uyakwazi ukumelana isiyobisi kakhulu kakuhle esebenzayo i samathambo nonspecific, ifiva etsolo samathambo, neuralgia, myalgia, arthralgia, isifo Bechterew kaThixo, ingqele, periodontitis. Le medicament kwakhona yenzelwe enkqonkqoza intloko, iintlungu wamazinyo, ukuxhuzula ifiva, iimpawu ukuphazamiseka exesheni.

Kuba "mefenamic acid" Kukho Izimo eziliqela, eliyinhloko kuzo phambi hypersensitivity lwesifo duodenal kwethumba kunye nesisu, izifo zesisu yokukrala igazi, zezintso. Ngexa lokukhulelwa, kufuneka lokwaphusa umda yi ukusetyenziswa kweli chiza.

Intsebenziswano kunye namanye amachiza kumaqela - inkalo enye, esibonakala mefenamic acid. Isikhokelo ukulungiselela ikuchaza ngokweenkcukacha zonke abasabela kunokwenzeka kunye iingxaki. Xa kunxityelelwana "Analgin" kunye salicylates eyomeleziweyo isiphumo anti-ukudumba. Ichiza kwakhona kwandisa ixesha prothrombin xa uthatha anticoagulants.

Imiphumo enkulu icala, nto leyo eye mefenamic acid, abavela disorder zesisu babecinga ngayo motor kunye nokuphazamiseka dyspeptic. Nokusebenzisa elide eli chiza ukuze aphuhlise uhlobo anemia hemolytic.