Ichiza "Proksium": imiyalelo ukusetyenziswa, nabalingani real

Indlela yokusebenzisa ichiza "Proksium"? Imiyalelo zokusetyenziswa ichiza ochazwe izinto nqaku. Kuyo uya kufumana ulwazi malunga kwifomu apho uthe medicament senziwa, ukuba wayenazo na analogue apho ukuze wamiselwa njalo njalo.

Imilo, ukupakishwa, ukwakhiwa iziyobisi

Ziziphi uhlobo oveliswa sisiyobisi njenge "Proksium"? Imiyalelo yokusebenzisa licebisa ukuba eli chiza luyafumaneka njenge amacwecwe ezimhlophe Imiqulu yekhadibhodi, kwakunye lyophilizate kunye ampoule wesinyibilikisi (10 ml).

Ifomu yokuqala ichiza ngokwayo iqulathe pantoprazole (40 mg), kwakunye izinto ezongezelelweyo. Malunga igutyana lyophilizate, ngoko kwakhona iquka 40 mg esisebenza + sodium hayidroksayidi.

Pharmacodynamics medicament

Ziziphi iinkalo na amayeza "Proksium"? Imiyalelo yokusebenzisa zibonisa ukuba lo anti-isilonda kunye antisecretory arhente.

Emva ezithatha ichiza ngaphakathi iibhloko kuyo imveliso zehydrochloric acid. Oku kwenzeka ngenxa yokuba ziyibuyisela umva le ngesenzo Proton ukuba isicelo, oko kukuthi iiseli parenteral esiswini.

Ichiza into esebenzayo ekwaziyo zokunciphisa carcinomas pentagastrin-kwavusa enzyme, ukutya kunye insulin, secretion esiswini. Ukongeza, ichiza abangaphangeliyo umsebenzi ebalulekileyo intsholongwane Helicobacter pylori. Njengokuba kubhaliwe awaziwa, ukwanda yayo esebenzayo bathi ukuyilwa izilonda kunye erosions kwi kwiinwebu iindonga isisu.

Ukongeza koku kungasentla, ingqalelo ichiza kwandisa ukusebenza kwezinye izinto elwa.

Pharmacokinetics beziyobisi

Yintoni chiza iipropati pharmacokinetic "Proksium"? Imiyalelo yokusebenzisa iya kwazisa izigulane malunga yokuba emva kwedosi yokuqala legalelo zeziyobisi ephuhlisa ngokukhawuleza kakhulu kwaye sihlala iintsuku.

Umxholo eliphezulu ichiza kwi plasma yegazi waphawula iiyure ezine emva kokuba efumene idosi umgangatho-40 mg. Ubungakanani kokubonisa kunye iiprotheni yi-98%. Ixesha isiqingatha ubomi ichiza ifikelela iiyure ezimbini.

Lithathwe neziyobisi ngokusebenzisa izintso amathumbu.

Pantoprazole ifunxwe emathunjini amancinci. Le bioavailability osisiqu nama-75%.

Yokucolwa amachiza isithako esisebenzayo esibindini. Xa oku kwenzeka i conjugation reaction, dealkylation kunye namachibi ne nxaxheba ngqo enzyme ezifana cytochrome P450.

Kufuneka kwakhona uqaphele ukuba ichiza ingqalelo ngokulula inqumle umqobo segazi lobuchopho. Ngaphezu koko, sibonakala lula ubisi lukanina.

Xa abadala, xi plasma kunye bioavailability beziyobisi iphezulu kakhulu kunaleyo izigulane abancinane.

Phambi kwesibindi kweziyobisi ingabhekiswa ofakwe iiyure 9.

Xa beqeqeshwe?

Ngoku uyazi indlela ichiza "Proksium". Imiyalelo yokusebenzisa, ukubuyekeza ichiza icebisa ukuba ezibonisa yayo ukusetyenziswa ziquka ezi zifo zilandelayo:

• izilonda esiswini 12 isilonda duodenal (kuquka amaxesha exacerbation);
• unyango lwe gciwane Helicobacter pylori (ukwamkela kuphela inxalenye unyango leqela);
• reflux esophagitis kunye Zollinger-Ellison syndrome;
• ukwandisa imveliso yesiselo esiswini;
• uhlobo mnene reflux esophagitis.

Awukwazi ukusebenzisa

naziphi Izimo has a neziyobisi "Proksium" (tablets)? Imiyalelo yokusebenzisa iya kwazisa izigulane ukuba olu hlobo beziyobisi kuyo nayiphi na imeko kufuneka ingamiselwa ukuba ngaba:

• ukusilela hepatic, kakhulu;
• nokukhulelwa;
• ezinezigulo xa amalungu phecana zesisu;
• lwebele;
• uxabana amacandelo amayeza;
• abantwana abangaphantsi kweminyaka eli-14.

Malunga umxube ezineengqayi, ayikhuthazwa tu into yokuba izigulane kunye kukwalisa "Pantoprazole". Ukongeza, le fomu amayeza kuyo nayiphi na imeko ayikwazi zidityaniswe kunye "ATV".

Tablets "Proksium": imiyalelo yokusebenzisa

Analogs beziyobisi anti-isilonda iza kwenziwa ekupheleni kweli nqaku. Kweli candelo, siza kukuxelela ngendlela eli chiza kufuneka athathwe phantsi izifo ezithile.

Xa kutyunjwa ichiza "Proksium" Oogqirha abaninzi lukhetha ifomu tablet. Ukuba isigulana na ingxaki yokuginya, isisombululo ke emiselweyo.

Le umthamo ichiza, kwakunye ukufumana indlela kufuneka imiselwe ngugqirha wakho kuphela.

Ngoko ukuba ayinonophele njani ichiza "Proksium 40"? YokuFundisa (tablet ethengisiweyo kuthetha ukuba wonke Pharmacy) ithi ukuba idosi abawacebisayo ichiza mg-40 ngosuku. Ichiza ethathwe ngexesha okanye emva kokutya, esela amanzi.

Xa ekuxilongweni isilonda esiswini okanye ukhukuliseko idosi yemihla ngemihla landile ukuya 80 mg.

Kuba unyango 12 iyeza isilonda duodenal ithathwe iintsuku 15-30. Ke ukuba reflux esophagitis, kunye izilonda esiswini, unyango lwezifo ezifana kufuneka abe ngaphezulu kweenyanga-2.

Ukuphelisa le ntsholongwane Helicobacter pylori isigulane 1 tablet kabini ngemini. Ngethuba lokuqhuba kwale nyango kwiiveki ezi-2.

Izigulane abaphethwe ukusilela kwezintso, kwakunye nabantu abadala idosi yemihla ngemihla akukho ilawulwa ngaphezu kwama-40 mg.

Xa sisibindi kunye namayeza kakhulu zesibindi kwesibindi uvumelekile ukuba uthathe 1 tablet yonke eminye imihla.

Isisombululo "Proksium": imiyalelo yokusebenzisa

Le ampoules Amalungiselelo loo omiselwe yolawulo ngomlomo akunakwenzeka.

Into igutyana equlathe lyophilisate igalelwe ml 10 isisombululo emzimbeni. Ezinye iingcali bacebisa isiyobisi enjalo ixubene phambili 100 ml-5% solution iswekile.

nokubandakanywa efakwa kuhlala imizuzu ubuncinane emibini (malunga ¼ kukhethwa hour).

Isisombululo ichiza kufuneka zisetyenziswe ngoko nangoko emva kokuba uxhulumaniso onke amacandelo. Ukuba oku asifuneki, ichiza kufuneka abekwe egumbini okupholisa kwaye isicelo ungadlulanga umhla ngaphezu kweeyure ezili-12.

Ubude therapy medicament ngoko azipilisi olufanayo. Ixesha ubuninzi unyango - iinyanga ezi-2.

Xa isigulo ezifana reflux esophagitis, ichiza elo lilawulwa isixa webhotile elinye yonke imihla.

Kuba unyango lwe ukopha okwenzeka endaweni isilonda 12 duodenal isilonda kunye nesisu nomhlaza kwakunye nokuthintela kakhulu, ichiza lisetyenziswa kunye ml 80 butofelwe (bolus).

Ukuqaliswa kwalo eboniswe neziyobisi infusomats usebenzisa 8 mg ngeyure nganye.

Xa Zollinger-Ellison syndrome kunye hypersecretion medicament emiselweyo mg 80. ugqirha kunokwandisa ithamo ukuya mg 160 xa kuyimfuneko. Kulo mzekelo, oku kufuneka ukuba bazohlule babe amathamo-2.

Ukuze ngokukhawuleza ukunciphisa ubumuncu yejusi esiswini, ngokuqhelekileyo usebenzisa 80 mg beziyobisi kabini ngemini.

amacala libanda

Ziziphi iimpawu kwenzeka xa amathamo ephezulu "Proksium" iziyobisi (40 mg)? Manual ithi ukuba iimeko ezikhoyo ezinjalo akukho miyalezo.

Xa ufakwe amayeza butofelwe (ubuninzi 240 mg) kukho ukunyamezeleka kakuhle. Ukuba usebenzisa isixa esikhulu ichiza, kuyimfuneko ukusebenzisa nokugcinwa ubuthi therapy.

Iingcali kubonisa kakuhle ukuba into libanda, "Proksium" iipilisi kungandisa amandla namatyeli yeziphumo ebezingalindelekanga. Kulo mzekelo, bayayeka ukuthatha iipilisi.

ukusabela ezingalunganga

Buhle angafuneki kungenzeka izigulane abafumana "Proksium 40" iziyobisi? Imiyalelo ithi ukuba ukusetyenziswa kwale isixhobo rhoqo kuphumela:

• kwesisu, iintlungu esiswini, urhudo kunye flatulence;
• cephalgia.

Ngamanye amaxesha, ebaphethe:

• ukurhawuzelelwa kunye nesikhumba irhashalala;
• ukuphalaza;
• arthralgia;
• kome ngenwebu yangaphakathi;
• zokuphila;
• belching;
• Angioedema;
• ubuthathaka kunye ukozela;
• nesiyezi.

Kwakhona, amatyala ezingaqhelekanga zilandelayo Kuye kwabikwa:

• ukudakumba, myalgia, Lyell syndrome, irhashalala, Stevens-Johnson syndrome;
• msebenzi enqanda zesibindi, nenyongo, hepatocytes ezonakeleyo, ifiva, nephritis;
• ubuntununtunu ekukhanyeni, thrombocytopenia, leukopenia;
• thrombophlebitis (enxulumene isisombululo kwenzeka kuyo inaliti);
• lafa, uvalo, ukuncipha ukuva umbono;
• amaqhakuva, alopecia, hyperglycaemia.

imithi

Zeziphi iimpawu ichiza kwisigulana ukwazi phambi kokuba uthathe iyeza "Proksium"? oku kuthetha myalelo ubonisa mpawu zilandelayo:

• amayeza kujongwa zinokudityaniswa kunye "Diclofenac" caffeine "glibenclamide" ethanol "phenytoin", "metoprolol", "diazepam" "nifedipine", "carbamazepine" "theophylline", "digoxin" kunye arhente zocwangciso hormone "naproxen" yaye "digoxin".
• It ayinqweneleki ukuthatha isixhobo kunye "ATV".
• anticoagulants enjalo coumarin njenge "phenprocoumon" yaye "Warfarin" nodibaniso 'Proksiumom "kungakhokelela ekubeni ekuncipheni PB.
• Akukho ngokwezonyango imithi ebalulekileyo with "metronidazole", "amoxicillin" yaye "clarithromycin" sele zichongiwe.
• Pantoprazole kunciphisa absorbability kweziyobisi, le bioavailability apho esinefuthe ngqo ixabiso le-pH yencindi yewayini esiswini (umzekelo, "Posaconazole", "ketoconazole" "Itraconazole" "Atazanavir", "Erlotinib").
• Ukudityaniswa kunye medicament njenge "MTX" kukhokelela ekwandeni ubuthi yokugqibela.

izincomo ezithile

Zeziphi iinkalo ichiza kufuneka azise ugqirha phambi kokunika isigulane eso amayeza akho njengoko "Proksium" (tablets)? IMimiselo ehlonyelwe kwesi medicament, ukufunda efunekayo. Yathi ukuba eli chiza aluvumelekanga ukuba abantu ukuqunjelwa luvo.

Xa kokufumana ichiza ngaphezu kweenyanga ezintathu, isigulane lisenokuba hypomagnesemia. Imiqondiso yesi sifo zezi: amahlaba, ukudinwa, tetany, ingqondo, isiyezi kunye ventricular arrhythmia. Kwimeko apho iimpawu ezinjalo amayeza kufuneka zipheliswe yaye ngoko nangoko udibane nogqirha wakho.

Phambi unyango kunye nasemva gastroendoscope yayo ukuvalwa ngokuyimfuneko wenziwe ukufumanisa imeko emathunjini. Kufuneka Makukhunjulwe ukuba pantoprazole kube lula kakhulu ukufihla iimpawu yobubi.

Ithamo liphezulu ngosuku abantu abakhulileyo kunye izigulane kunye ukuphazamiseka kwi ezintso-40 mg. Izigulana kwesibindi yonke imihla amayeza kufuneka licuthwe ngesiqingatha.

Therapy ujongene indlela, kwiimeko ezinqabileyo, kukhokelela kuphuhliso campylobacteriosis kunye salmonellosis.

Impompo Proton inhibitors kwandisa umngcipheko kwamathambo kwi abadala nge (ixesha elide unyango) malunga ne-30%.

Analogs kunye Izithethantonye neziyobisi

Ngoku uyazi ukuba yintoni na nendlela ukuthatha ichiza "Proksium". ukusetyenziswa kwale ndlela ekufundiswa kuchazwa ngokweenkcukacha ngasentla.

Ukuba nangasiphi na isizathu ichiza a engavumelani nawe, kokuba kufakwe kunezixhobo oqhelekilyo, njengoko "Barolo", "Emanera", "Geerdin", "esomeprazole", "Diaprazol", "Ortanol", "Nexium", " rabeprazole, "" Veloz "," Sanpraz "," lansoprazole "," Ezolong "," Gasek "," Ultop "," Deksilant "" Pariet "," Zulbeks "," omeprazole "," Omelik "," Ozol " "Losek", "Omez", "uEpicurus", "Omealoks".

Kwakhona, ichiza "Proksium" kuthetha kukho iziyobisi-izithethantonye "Kontrolok", "Pantazi", "Panzol", "Panum", "Nolpaza", "Penta", "Pantex", "Pultset", "Ultera".

Izimvo medicament

Phantse zonke ukubuyekeza amayeza zithathwa HIV. Izigulane bathi ichiza "Proksium" ikhuthaza ukuphilisa ngokukhawuleza erosions nangenxa yezilonda, kwakunye iyaluthintela uphuhliso likakade.

Ke ukuba ziziphumo ebezingalindelekanga, izigulana ezininzi ngokuqhelekileyo wabonakalaliswa iquka isicaphucaphu kunye neengxaki esitulweni.