"Kalchek": imiyalelo ukusetyenziswa, analogs, ncomo

Oko umele ukwazi phambi kokusebenzisa eli chiza, njengoko "Kalchek"? Imiyalelo yokusebenzisa iziyobisi zokufunda ezifunekayo utshilo. Kuyo uya kufumana ukwalatha kunye Izimo ukuba ukusetyenziswa kwale kweziyobisi, kwakunye ufumanise ukuba unayo nayiphi na analogue kunye neziphumo ebezingalindelekanga.

Ifom yokuxhoba, ubume kunye nokupaka

Ngaba uyazi ifomu apho unokuthenga ichiza "Kalchek"? Imiyalelo yokusebenzisa yazisa ukuba ichiza ifumaneka kuphela azipilisi. Ukubunjwa medicament iquka esisebenza ezifana amlodipine besylate (5, 2.5 no-10 mg). Ngokuphathelele izinto ezongezelelweyo, ngoko ke ziquka dibasic calcium phosphate, umbona starch, isodiyam wesitatshi glycolate, talc nyulu, dust colloidal kunye wemagniziyam stearate.

Amacwecwe ezi blister (10 iiPC.), Yiyiphi zibekwe kwibhokisi eyenziwe yekhadibhodi.

Iimpawu amayeza kwisixhobo yezonyango

Njani amayeza "Kalchek"? Imiyalelo Sebenzisa ithi ichiza a uyakhetha calcium channel blocker kwiklasi yesi-2. Uye antianginal, umfutho, vasodilating, kunye neziphumo antispasmodic. izinto zamachiza ifakiwe ukwakhiwa kwale iarhente, ekwaziyo uvimba ukuhamba ion calcium kwizisele nemithambo umsipha egudileyo.

iipropati Anti-unesifo beziyobisi ngenxa isiphumo yayo ngqo Ukunyenyiswa kwi nemithambo egudileyo kwezihlunu. Ngokumalunga isiphumo anti-anginal, lo medicament uchaphazelekayo akwazi ukwandisa arterioles (peripheral). Kamva, oku kukhokelela ekuncipheni nokumelana peripheral semithambo, nto leyo yenza ukuba kubekho ukwehla kwemfuno engabalulekanga ukuba O ₂ (oksijini).

Nakuba kunjalo, kufanele kuqatshelwe ukuba ngamanye amaxesha isenzo oku kuthetha ioksijini, phezu koko, landa. Oku kungenxa yokwanda kwemithambo yenhliziyo (umz, angina vasospastic).

Kufuneka kuqatshelwe ukuba cwecwe "Kalchek" akukho iziphumo ezibi lipid nokwakheka igazi. Bakuzuze umsebenzi antithrombotic kwaye antiatherosclerotic, ukunyusa izinga ukuhluza (glomerular), kwaye kananjalo zibe nefuthe eliqhelekileyo natriuretic.

Xa nephropathy isiyobisi seswekile ayikwazi ukwenza yokwanda microalbuminuria.

Iimpawu pharmacokinetic ye ichiza

Apho kukufakwa ichiza "Kalchek"? iingcali Guest zibonisa ukuba kukufakwa ichiza livela lokugaya (malunga 90%). ingqondo yakhe omkhulu egazini emva kweeyure 7-12. Le bioavailability beziyobisi yi malunga 63-65%.

I engekho mthethweni esebenzayo ingena umqobo igazi-ingqondo kwaye kwizondlo ubisi lwebele. Amlodipine biotransformed esibindini (metabolites engasebenziyo kwakheka).

Xa imveliso singaguqukanga engaphantsi kwe-10% ye-kuqulunqo. Ngokuphathelele metabolites abapholileyo, ziboniswa kwi-mali ka-60% kwi umchamo, yaye malunga 20-25% ngu amathumbu kunye kunye inyongo.

Ubungqina obubonakalayo buxela

Ziziphi izifo a iipilisi isigulane "Kalchek" linokukwenziwa? Imiyalelo yokusebenzisa (ngokufanayo kwisixhobo eboniswe ngezantsi) inika ingcaciso okukhomba zilandelayo:

• angina ezinzile;
• angina eziguquguqukayo;
• umfutho wegazi (esetyenziswa monotherapy okanye kunyango kunye inhibitors ACE, womchamo thiazide, beta okanye alpha blocker);
• angina angiospastic (okanye ekuthiwa Prinzmetal angina).

Izimo

Xa phambi kwawo nawuphi na umqathango isigulane kufuneka ukuba iipilisi "Kalchek"? Imiyalelo yokusebenzisa iqulethe ezi Izimo zilandelayo:

• hypotension wegazi;
• Hypersensitivity ukuba amayeza eziphambili into esebenzayo.

Kufuneka kuqatshelwe ukuba ichiza ayikwazi ingasetyenziswa kwizigulane abaye babe hypersensitivity ukuba dihydropyridine yezabelo.

Drug "Kalchek": imiyalelo yokusebenzisa

Tablets "Kalchek" angina kunye noxinzelelo lwegazi ziqhutywa ngendlela umthamo 5 mg ngosuku. Ukuba kuyimfuneko, angandiswa ku-10 mg.

Izigulane une cardiomyopathy inimba, nokunyanga kunye iidosi ka 2.5 mg ngosuku. Ukuba ichiza ukunyamezeleka ngokwentelekiso kakuhle, kunokwenzeka ukuba kancane ithamo (hayi ngaphezulu kwe-10 mg ngosuku).

Xa isicelo iipilisi njengoko kufuneka njengenxenye yonyango indibaniselwano ne beta-blocker, womchamo thiazide okanye ACE inhibitors hlengiso lwe kwirejimeni nomthamo.

Iimpawu ze libanda, kunye nonyango inkqubo

Ziintoni iimpawu libanda, zenzeka xa idosi ephosakeleyo amayeza "Kalchek"? Analogue kunye ichiza ngokwayo kunokubangela ucaca hypotension. Njengoko unyango isigulane kufuneka anikwe isikhundla oxwesileyo, aniphakamisele kancinane imilenze yakhe. Ukongeza, imfuneko ukuxhasa umsebenzi iimpahla ngentliziyo negazi, iliso izalathi si zokunikwa umsebenzi yemiphunga kwenkqubo, kolawulo diuresis kunye BCC.

Ukubuyisela nemithambo ithowuni isigulane unikwa amachiza vasoconstrictor. Ukunciphisa iimpembelelo calcium channel yaye kuvalwe, isigulana ilawulwa (i.v.) calcium gluconate.

imithi

iipilisi ngaxeshanye "Kalchek" yaye "Warfarin" ichiza akubangeli utshintsho olubalulekileyo kwixesha prothrombin xa abameli onempilo oyindoda womelele.

Xa usebenzisa zombini medicament ingqalelo kunye namayeza 'digoxin "Kuye kubekho utshintsho egazini uyondelelwano lwee- yokugqibela, yaye zavunyelwa yayo sezintso.

Ulawulo ngaxeshanye iziyobisi "Kalchek" yaye "Cimetidine" alunasiphumo kwi iimpawu pharmacokinetic of amlodipine.

Ukukhulelwa ne zisanyisa

Nokuba kunokwenzeka ebudeni "Kalchek" amacwecwe lokwaphusa kunye kokumitha yokuziphatha njani ukwamkelwa kwawo? Imiyalelo yokusebenzisa, oogqirha yokwenene ukwazisa ukuba ukusebenza kunye nokhuseleko eli chiza ngexa lokukhulelwa kunye nencum-ukondla usana lwakho lingakulungele.

imiphumela emibi ichiza

Yintoni iziphumo ebezingalindelekanga kunokubangela iipilisi 'Kalchek "? Imiyalelo yokusebenzisa esi sixhobo kungqina ukuba ukuqeshwa kwakhe ukuze baxabane ezingafunekiyo emzimbeni. ingakumbi phakathi kwazo zezi zilandelayo:

• Imikhumbi nentliziyo, ukuphelelwa umoya, iyangongoza, kunye ukufikelwa.
• I-luvo (neuropathy central): cinca-cinca, isiyezi, amahlaba kwezihlunu, intloko ebuhlungu, ukungaboni, ukozela, asthenia, ukudinwa, paresthesia kunye myalgia.
• wokugaya: iintlungu esiswini, ukuqunjelwa, senyongo cholestatic, isicaphucaphu, ukwanda transaminases (kwesibindi).
• Ulusu: erythema multiforme, pruritus, angawokubhuda.
• Okunye: hyperplasia gingival, gynecomastia, yokubakho qho ukuchama, namandla kunye ukudumba.

imiyalelo ezikhethekileyo ngokufumana ichiza

Luhlobo olunjani bokuqonda ingqalelo ichiza kufuneka uyazi phambi kokuba uqhubeke ukuthatha iipilisi 'Kalchek "? Iingcali Guest bathi olu nyango kufuneka zisetyenziswe ngononophelo kakhulu kubantu umsebenzi kwesibindi kakuhle, ngokunjalo ukusilela intliziyo (chronic) kunye stenosis aortic.

ukwamkelwa ngaxeshanye amayeza "Kalchek" kunye arhente non-steroidal, nitrate, amachiza kunye namayeza hypoglycemic (oral) kunokwenzeka.

Amava yokusetyenziswa bezonyango beziyobisi abantwana abaselula engekhoyo.

Tablets "Kalchek" kuba nafuthe ubuchule yesigulane ukuqhuba imoto.

Imigaqo nemiqathango nokugcinwa ichiza

Ukulungiselela "Kalchek" (5, 10 no 2.5 mg) kufuneka zigcinwe kwindawo ebandayo, eyomileyo, omnyama ingafumaneki abantwana abancinane. Ithuba lokugcinwa amacwecwe yiminyaka-2.

Ukuphonononga imveliso amayeza, kwaye iindleko analogue yayo

Yintoni indawo isixhobo ezifana 'Kalchek "? Analogs kweli chiza ziyafumaneka phantse kuzo zonke drugstores. Phakathi arhente zixhaphakileyo ziquka imithi zilandelayo: "Agen", "Tenoks" "adipic", "Stamlo", "Akridipin", "Omelar Cardio", "Amlo", "normodipin" "Amlodipine" "Norvasc" "Amlovas", "Amlorus", "Norvadin", "Amlodigamma", "Cordy Kor", "Amlodhi", "Korvadil", "Amlodifarm", "Karmagip", "Amlokard-Sanovel", "cardilopin", "Amlong" "Vero Amlodipine", "Amlotop", "Amlonorm".

Yintoni ixabiso mali? Amaxabiso avareji ichiza 175-190 engange Russian (5 mg, amacwecwe 30).

Ngokumalunga izimvo zezigulane, ukuba elincumisayo becala. Ngokutsho kwabo wakha isicelo iyeza, ngokuphumelelayo ulwa kunye angina kunye noxinzelelo lwegazi. Kufuneka kuqatshelwe ukuba inani elikhulu lezigulane obonwabisayo yokuba le ichiza ukunyamezeleka ngokwentelekiso kakuhle ngawo. Nangona kwezinye iimeko ipilisi "Kalchek" zisabangela iziphumo ebezingalindelekanga ezifana yintloko, iintlungu esiswini, isiyezi, isicaphucaphu kunye kukwalisa apha esikhumbeni.