"Kaffetin Cold": imiyalelo ukusetyenziswa, ukubunjwa, analogue

Yintoni unyango "Kaffetin Cold"? Yenziwe ngoobani kunye iimpawu ichiza kuya kuxoxwa ngezantsi. Siyakutsho Kwakhona nawe ukufumana njani wathi medicament kwaye yintoni izifo kokuba kumiselwe.

Imilo, ukupakishwa, ukubunjwa

Le medicament "Kaffetin Cold" sele ithunyelwa azipilisi kunye nemilo biconvex lume (umgca kwicala elinye) wawutyabeka blue umboniso-camera. Bona wabekwa blister tubing, equka ngefoyile ye-aluminiyam ze umaleko ezintathu-oluselubala umboniso, leyo kwibhokisi ibhokisi.

Oko iqulethe neziyobisi "Kaffetin Cold"? Ukwakhiwa kwale isiyobisi:

• dextromethorphan hydrobromide (15 mg);
• pseudoephedrine hydrochloride (30 mg);
• ascorbic acid (60-62 mg) njenge granulate, oluqulathe 97% of vitamin C, no-3% hydroxypropyl methylcellulose;
• paracetamol (500-555 mg) ngokohlobo granules equka 90% ukwimo, kwakunye amacandelo abangabancedani prozhelatinizirovanogo starch stearic acid kunye povidone.

Kufuneka kuqatshelwe ukuba i "Kaffetin Cold" njengokuba izinto ezongezelelweyo ziquka wemagniziyam stearate, dust colloid, microcellulose, isodiyam croscarmellose kunye talc.

Film enamathela le medicament wenziwe idayi emsi, macrogol, titanium dioxide, Polyvinyl utywala kunye talc.

Kwemithi beziyobisi

Ziziphi iimpawu ezi uphawu amacwecwe 'Kaffetin Cold "? Imiyalelo ithi ukuba isixhobo uyakwazi ukubonisa iintlungu kunye neempawu antitussive.

Indlela yokusebenza ye medicament ngenxa yobukho kuwo zezakhi ngasentla. Cinga iimpawu zabo ngoku:

• I-paracetamol kuchaphazela umzimba kunye obezbolivayusche zharoponizhayusche. Le element uyakwazi ukuvala Cox kwi CNS. Oku kwenzeka ngokusebenzisa neziphumo ngqo kumaziko intlungu thermoregulation.

Olona phawu olwahlula le eziletha NSAIDs kukungabikho iyonke legalelo anti-ukudumba. I-paracetamol a ukubacaphukisa wokugaya kwaye aluchaphazeli nethe ngamanzi-ityuwa, njengoko loo nto kakubi aluchaphazeli Yindibanisela prostaglandins zomzimba peripheral.

• Yintoni na iziyobisi ephawulekayo "Kaffetin Cold"? Ukukhutshwa pseudoephedrine liyakwazi ukunika impembelelo tapered kwi iimpahla ukuba xa isifo i pharynx nakumarhanana. Kwakhona, le ngxenye kakhulu kunciphisa ukudumba, ngaloo ndlela kuncitshiswa secretion kwi nasopharynx kwaye lula samarhanana uphefumlayo.
• Ascorbic acid uqulathwe ku isithuthi, nokuhlawulwa ivithamin C ngxaki, nto leyo sivame ngexesha njengomkhuhlane.
• Dextromethorphan kuchaphazela iziko khohlo. Oku kunciphisa ubungqongqo ukhohlokhohlo womileyo inxulunyaniswa kwinwebu le nasopharynx uxakaxa ukuba ifiva.

iipropati kinetic

wenza kukufakwa ichiza "Kaffetin Cold" Njani? iingcali Ukuphonononga zibonisa ukuba ukufunxeka ezininzi paracetamol lwenzeka kwi emathunjini amancinci. Ngaloo eyavela liphezulu kwi plasma ngegazi wayiphawula phakathi kwemizuzu 30-90 emva ulawulo ngomlomo.

Nethe osisiqu ekuthethwa (malunga 90-95%) yenzeka esibindini. Ngenxa yoko, avela abapholileyo bayazibhijabhija (ngenxa indlela conjugation kunye glucuronic acid kunye sulfates). Ukuze babe nempembelelo uvimba kwinkqubo enzyme zesibindi, kwakunye ukuba bawaphikise ukufa iiseli.

Isiqingatha-bomi candelo ngabantu ziiyure 1-4. paracetamol wabonisa metabolites yayo yi nezintso. Ebudaleni inokuba ukuhla imvume ichiza, kwakunye nokwanda ngexesha kwisiqingatha-ubomi.

Emva dextromethorphan bangena emzimbeni womntu, yena phantse nangoko yangena egazini. Ukufumaneka kakhulu lwesi sakhi kwi plasma emsebenzini emva kwemizuzu 130 ezingengaphi emva kokuthatha iipilisi. Le into umzimba esibindini. metabolites yayo idubule ingeka yokuchama.

Pseudoephedrine wafunda ngokukhawuleza kulo kwegazi emva ulawulo ngomlomo. Ukufumaneka eliphezulu iziyobisi iyazalisekiswa emva malunga 2 iiyure plasma. Half-ubomi pseudoephedrine yi ngeeyure eziyi-6. It umzimba esibindini (inxalenye), ngaloo ndlela yakheka ithe leyo kamva kwazona kwi yokuchama.

Njengoko le acid ascorbic, oko ako kakuhle ukusuka iphecana zesisu kwaye zasasazwa ngokukhawuleza kuzo zonke izihlunu. Eli candelo reversibly oxidized ukuba degidroksiaskorbinovoy acid. Kulo mzekelo ezinye ivithamin C ezifunyenwe yi umzimba, umzimba kwi element ekuthiwa ascorbate-2-sulfate.

Idubule iziyobisi livela yokuchama.

ubungqina

Drug "Kaffetin Cold" isetyenziselwa unyango kwangumqondiso influenza kunye iingqele, kubandakanywa kukuvela iimpawu mnandi, ezifana intloko ebuhlungu, ukhohlokhohlo owomileyo, iintlungu kwezihlunu, iintlungu emqaleni, impumlo esihambisayo, ifiva, sinuses ngeempumlo kunye nempumlo .

Izimo

Drug "Kaffetin Cold" ayikwazi ingasetyenziswa kwizigulane kunye nale miqathango ilandelayo:

• nokukhulelwa;
• Hypersensitivity ukuba ichiza;
• ukungabi naso glucose-6-phosphate dehydrogenase;
• lwegazi, isifo sentliziyo, sifuba angina;
• ukuphazamiseka kakhulu kwi wezintso kwaye wesibindi, hepatitis;
• ukwamkelwa ngaxeshanye lakhula, monoamine oxidase inhibitors neziyobisi esetyenziswa ukunyanga antiparkinsonian;
• zisanyisa;
• yobudala engama-12.

Ukuqapha ke iyeza kucetyiswa ukuba:

• arrhythmia;
• hyperbilirubinemia ebubonisayo;
• hyperthyroidism;
• hepatitis load;
• hyperplasia ngayo le ndlala wendlala;
• utshwala;
• iswekile osegazini;
• obstructive isifo pulmonary uhlobo ezingapheliyo;
• isifuba inyumoniya;
• ukukhathala.

Medicament "Kaffetin Cold": imiyalelo yokusebenzisa

Izincomo kuthethwa bujolise kuphela nolawulo ngomlomo.

Esithathwa abadala kunye nabafikisayo ukususela kwiminyaka eli-12 ubudala yi-1 icwecwe kane ngemini. Ngelo xesha uvumelekile ukuba asebenzise hayi ngaphezulu kwe amacwecwe-2.

kufuneka ibe ngaphantsi kwe iiyure 4 Ixesha lokuphumla phakathi abasebenzisi amayeza. Ngaloo ndlela idosi yemihla ngemihla ichiza mayingagqithi iipilisi 8.

Ukuba kukho fever iintsuku ezingaphezu kwe-3 emva kokuba unyango, kunye ukhohlokhohlo elomileyo kulwa iintsuku ezi-5, ngoko kufuneka ngoko nangoko ufune uncedo lonyango.

icala izenzakalo

reactions Ezingalunganga emva ezithatha ichiza phantsi ingqalelo ibonakalaliswe ngeendlela ezininzi, phantse kuzo zonke amalungu kunye neenkqubo umzimba:

• isicaphucaphu, umlomo owomileyo, iintlungu epigastric;
• somnolence, ukuphazamiseka, ukuba nochuku, isiyezi;
• komzimba njengoko pruritus, irhashalala, angioedema, urticaria;
• noxinzelelo lwegazi, uphuhliso tachycardia;
• anaemia, thrombocytopenia, agranulocytosis, pancytopenia;
• ukusebenza nephrotoxic, nto leyo ebonakalisa yokulunywa kwezintso, uphuhliso necrosis papillary okanye nephritis Embi.

An libanda, imithi

Xa amathamo aphezulu ichiza, umguli bangase isicaphucaphu, ukuduma kunye neentlungu esiswini. Kwakhona kabi kwemfuneko iidosi ulusu yesigulane iba libunile, liphuma kunye umbilo iba iyangongoza rhoqo.

Kuchazwe ifuna ngokukhawuleza ukugungxula isisu. Kwakhona, ithamo elawulwa kwisigulana iyasebenza carbon, ubunzima izigulane ezifanelekileyo. Ukuba kuyimfuneko, uthomalaliso nomqondiso.

intsebenziswano

I-paracetamol ngeedosi eziphezulu kwandisa imiphumo anticoagulants.

Ukusetyenziswa kweziyobisi ezo inducers of microsomal igcwala (umz: "Phenytoin", ethanol, barbiturates, "rifampicin", "phenylbutazone", lakhula tricyclic), kunye arhente hepatotoxic kakhulu kwandisa ukuyilwa iimveliso esebenzayo hydroxylated pathways of paracetamol, nto leyo eyandisa amathuba Development kakhulu ukunxila , kubandakanywa ukwamkelwa iingedosi ezincinane iziyobisi.

ukusetyenziswa elide barbiturates kunciphisa ukusebenza paracetamol.

Iindibaniso paracetamol kunye salicylates kwandisa umngcipheko wokuhlaselwa ngumhlaza womlomo esinyini okanye izintso.

ukusetyenziswa elide NSAID kunye paracetamol ikhuthaza ukwenzeka iintlungu nephropathy, necrosis sezintso papillary kwaye kakhulu ngakumbi ukuphela-sigaba ukusilela kwezintso.

Besebenzisa "diflunisal" kukhokelela isiphumo hepatotoxic olufanelekileyo lwechiza.

usebenzisa lwe pseudoephedrine kunye nezinye arhente sympathomimetic inokuba negalelo kukuvela neziphumo zinetyhefu, kwaye ube nesiphumo additive. Indibaniso eli candelo kunye monoamine oxidase inhibitors kukhokelela kuphuhliso lobunzima unesifo. Kulo mba, ukusetyenziswa kweziyobisi ethathelwa ingqalelo zivumelekile ngaphambi kweentsuku ezili-14 emva kokufumana monoamine oxidase inhibitors inqanyulelwe.

usebenzisa of "Propranolol" iphucula isiphumo pressor leyo pseudoephedrine. Ngaphezu koko, xa usebenzisa lo wokugqibela kuncitshiswa isiphumo iqinile izixhobo ezifana "methyldopa", "reserpine", "mecamylamine" kunye t. N.

ulwazi oluthile

Ngoku uyazi ukuba lo neziyobisi "Kaffetin Cold."

Methamphetamine - is methamphetamine. Kuyinto ivuselela yaye ebangela ukuxhomekeka eliphezulu ngokunxulumene noko ezinxulumene neziyobisi. Abanye abantu abazama ukuzisa eli candelo beziyobisi "Kaffetin Cold." Isithuba phakathi beziyobisi eziveliswa ngeendlela ezahlukeneyo. reception kubangela imincili kwaye kuchaphazela ngokungalunganga zonke iinkqubo kunye namaziko.

Ngexesha unyango, ichiza kufuneka ukuba kukho imfuneko esweni imeko yomsebenzi kwesibindi yesigulane, kwakunye izalathi si zokunikwa igazi yoluvo.

Kuyo yonke le unyango isigulane Akuvunyelwe ukuba ukusela utywala, njengoko oku kungadala hepatotoxicity inyathelo iziyobisi. Kukwanjalo uya kuba izixhobo caffeine kunye nemveliso.

iyeza kujongwa iba nefuthe ngqo ubuchule yesigulane ukuqhuba kwezithuthi ze benze nayiphi na eminye imisebenzi ezifuna yoxinaniso ephezulu ingqalelo.

Drug "Kaffetin Cold": shiya ezikhemesti

Ngenxa yokuba le iyeza isoloko isetyenziswa ichiza, ekhululwe kuphela xa ntetho lokumiselwa kagqirha. Ngendlela, ukuba ukufumana loo ichiza ezikhemisti kunzima kakhulu. Kudla ukuba ithe yanikezelwa emva kokuba pre-oda.

amachiza afanayo

Zininzi indlela leyo kutshintshwa beziyobisi umbuzo. Ethandwa kakhulu ziquka ezi zilandelayo: "Amitsitron Forte", "Antigrippin", "bol-Abaleke Premium", "Vokasept", "Gripgo", "Gripkold-N", "Gripotsitron Forte", "Gripflyu", "Dolar", " H Cold "," Koldreks "," Koldfri "," Lemsip Lemon "," Novalgin "" kazz ezongezelelweyo "," Rinzai "," Tamipul "," Farmatsitron "kunye nabanye.