Analogs "Coraxan": Inkcazo kunye nemiyalelo yokusebenzisa

Yintoni analogue le "Coraxan"? Impendulo yalo mbuzo inokufunyanwa kwi izinto kweli nqaku. Ukongeza, siza kunika ulwazi malunga nento efunekayo ichiza njengoko kumele kube njalo-njalo.

ingcaciso jikelele ngale mveliso amayeza

Tablets "Coraxan" zimela ichiza anciphise izinga intliziyo. Le medicament iqulethe ngoqobo yayo esebenzayo kuqamba ezifana ivabradine hydrochloride, kwakunye amacandelo abangabancedani monohydrate lactose, nemagnesium stearate, umbona starch, maltodextrin, kwaye colloidal lesilicon dioxide.

imiphumela kwemithi

Analogs "Coraxan", yaye wathi nokulungiselela ngokwayo ukulawula izinga intliziyo ngenxa bakhethe yaye ethile sinus node ziyibuyisela UKUBA lamajelo, nayo elawula depolarization kulogo ukuzala. esisebenza yomenzeli onesiphumo kwi atrio-ventricular kunye neendledlana intraventricular, kwakunye ventricular repolarization kunye contractility engabalulekanga.

Ukongeza, ivabradine hydrochloride angasebenzisana ngemizila zabo retina, ezifana senhliziyo XA-imijelo, aqukiweyo ukwenzeka utshintsho Ukunakana into ebonwayo okwethutyana. Noko ke, lo msebenzi osemqoka engundoqo arhente amayeza i deceleration ubuchule ireyithi kwentliziyo.

Ezibonisa amayeza

Kutheni ukusetyenziswa analogue "Coraxan" kwaye zimelwe ngokusebenzisa ngokwawo? La machiza athe achazwa kwezi meko zilandelayo:

• angina izinzile. Therapy kwesi sifo encediswa esi sixhobo lwenziwa izigulane sinus isingqisho abaqhelekileyo kwi phambi Izimo nobandlululo ukuya beta-blocker, kwakunye ile kunye nabo.
• Ukungaphumeleli Heart (chronic). Nale ukungahambisani yokuxhoba ngokwalo kunye analogue "Coraxan" lisetyenziswa ukunciphisa izehlo iingxaki sentliziyo. Ngapha koko, inkoliso yawo abafe kwizigulane kunye izifo ezinjalo.

Izimo ukuba ukusetyenziswa kweziyobisi 'Coraxan "

Drug analogue "Coraxan" Bathe ke iyeza kufuneka ingasetyenziswa kwezi meko zilandelayo:

• hypersensitivity ku ivabradine hydrochloride, okanye nayiphi na amacandelo umenzeli oluncediswayo;
• angina eziguquguqukayo ;
• yashiya cardiogenic;
• bradycardia (ngamanye nezihlandlo izishunqulelo intliziyo, nokuphumla, ka ibetha ngaphantsi kwe-60 ngomzuzu e);
• iposi engabalulekanga (yondele);
• ukusilela hepatic (elimandundu);
• kakhulu hypotension (uxinzelelo lwegazi ngaphantsi kwi mmHg 90 kwaye iDiastolic - ngaphantsi kwe-50 mm HG ....);
• sinus;
• phambi kwe-ntliziyo;
• ibloko sinoatrial;
• Ukukhulelwa ne zisanyisa;
• ibloko atrioventricular degrees 3;
• usebenzisa of inhibitors elinamandla isoenzymes cytochrome (umz, iziyobisi "ketoconazole", "Erythromycin" "Itraconazole" "Josamycin" "Clarithromycin," "Ritonavir", "telithromycin" "Nefazodone" yaye "Nelfinavir");
• ebuntwaneni (ukhuseleko kunye nokusebenza kwale iyeza ukuya kwiminyaka eli-18 ubudala sele ukuba kufundwe);
• nobandlululo lactose.

Kwathathwa ngokuqaphela okukhulu!

Medicament "Coraxan" (ixabiso, analogs kule mali iya kunikwa ngezantsi) kufuneka isetyenziswe kuphela kagqirha. Ngononophelo kakhulu, ezifana iipilisi kufuneka zithathwe nge:

• sisibindi (nendawo);
• kululwa QT (iziphene) lokuphumla;
• ukusilela kwezintso (elimandundu);
• Ulawulo ngaxeshanye iziyobisi niyolule QT lekhefu;
• ukusetyenziswa ngaxeshanye juice grapefruit kunye cytochrome isoenzymes inhibitor;
• iphula nazimpawu umsebenzi ventricular ekhohlo;
• ibloko atrioventricular degree 2;
• stroke (kutshanje ufuduka);
• nombala semehlo (yamehlo ayo);
• hypotension;
• Ulawulo ngaxeshanye blocker channel calcium (umz, njengendlela "Diltiazem" okanye "Verapamil").

Drug "Coraxan": imiyalelo yokusebenzisa

Analogs kusho bacinga ngokukhulu iidosi efanayo kunye neendlela zokusebenzisa ukuba igama medicament. Kodwa ngaphambi kokuba uwasebenzise, qiniseka ukuba uwazi imiyalelo esiqhotyoshelweyo uze udibane nogqirha.

• Nge angina izinzile iziyobisi inxaxheba idosi lokuqala ibhalwa isixa-10 mg ngosuku. Ukuba emva kweeveki 3-4, umphumo therapeutic ekungazange kubekho injengayo, idosi yemihla ngemihla kufuneka kwandiswe ukuze mg-15 ngosuku.
• In ezingapheliyo sisifo sentliziyo arhente enjalo kwedosi yokuqala ibhalwa isixa-10 mg ngosuku. Ukuba emva-iiveki ezi-2 ukusebenza zonyango kwaye akezi, idosi yemihla ngemihla kufuneka lenyuke ku-15 mg ngosuku.
• Izigulane abaminyaka yobudala eyi-75 ekucetyiswa ithamo kokuqala 2.5 mg kabini ngemini. Kwixa elizayo, ungenza ukwandisa ithamo ichiza.
• Xa umsebenzi sezintso kwizigulane ezilawulwa iziyobisi "Coraxan" xa kukho imali mg-10 ngosuku. Ukuba emva kweeveki 3-4, umphumo therapeutic ekungazange kubekho injengayo, idosi yemihla ngemihla kufuneka kwandiswe ukuze mg-15 ngosuku.
• Ukuba umsebenzi isibindi ezingaqhelekanga izigulane ezilawulwa iziyobisi "Coraxan" xa kukho imali mg-10 ngosuku. Ukuba emva kweeveki 3-4, umphumo therapeutic ekungazange kubekho injengayo, idosi yemihla ngemihla kufuneka kwandiswe ukuze mg-15 ngosuku.

ziphumo bezingalindelekanga kunokwenzeka emva ezithatha ichiza

Nangona ngempumelelo, asinguye wonke umntu iingxaki zentliziyo ungxamile ukuthatha ichiza. Okokuqala, oku kungenxa yokuba wehlelwa ziziphumo ebezingalindelekanga:

• ukungaboni kwaye rhoqo utshintsho photoreception (okanye ekuthiwa photopsia).
• Bradycardia, sinus arrhythmia, arrythmia ventricular, angina (unstable), iyangongoza, iposi engabalulekanga, hypotension, extrasystoles supraventricular, fibrillation atrial, tachycardia ventricular, kunye ischemia engabalulekanga.
• Urhudo, isicaphucaphu nokuqunjelwa.
• Yintloko (ingakumbi ngenyanga yokuqala zonyango), isiyezi, ukuphelelwa umoya, amahlaba kwezihlunu, vertigo kunye syncope.
• Hyperuricemia kunye eosinophilia.
• Irhashalala, angioedema, pruritus, urticaria kunye erythema.
• Asthenia, umkhuhlane nokudinwa.

Drug "Coraxan": ncomo, analogue iziyobisi

Abo musa ukusebenzisa isixhobo kwakhona, ndithetha ngayo ezintle kuphela. Nangona kunjalo, eli chiza nto ibiza kakhulu. Ngoko ke, ngokuba kumacwecwe amayeza 56 "Coraxan" kuya kufuneka ukuba uhlawule malunga 1,200 engange Russian. Kulo mba, uninzi lwezigulane kunye nesifo sentliziyo ziqala ukuba analog zitshiphu beziyobisi.

I-analogue noshowo oku sixhobo ngenxa arhente esebenzayo ziquka amayeza zilandelayo:

• "Ivabradine hydrochloride";
• "Ivabradine".

Ngokutsho isiphumo enyangayo (amachiza ezenzelwe ukunyanga angina)

• "Amlodipine";
• "Asparkam";
• "Atenolol";
• "Aspirin Cardio";
• "Betalok";
• "Validol";
• "Hypoxen";
• "Izoket";
• "Diltiazem";
• "Izolong";
• "Carvedilol";
• "Concor";
• "Korvitol";
• "Lokren";
• "Cordipin";
• "Kunamandla Corinfar";
• "Metoprolol";
• "Mildronat";
• "Monosan";
• "Nitroglycerin";
• "Papaverine";
• "Nitrong";
• "Nifedipine";
• "Normodipin";
• "Plavix";
• "Prestancia";
• "Stamlo";
• "Sustonit";
• "Trimetazidine";
• "Tenoks";
• "Egilok";
• "Efoksa Long" njalo njalo.