Togu "chloramphenicol" sorhudo (tablets). "Chloramphenicol" (wamehlo) analogs

Uninzi lwethu luqhelene iimpawu ichiza "Chloramphenicol", apho ungakwazi ukumelana izifo ezahlukahlukeneyo. Kuyinto olusebenzayo izifo zesisu ezosulelayo, kuquka abo zikhatshwa sorhudo, zisetyenziswa kakhulu xa kusenziwa lwamehlo kwi umyalezo iintsholongwane zesi sifo. Noko ke, akusoloko sigwetyelwe ukusetyenziswa kweli chiza, ngoko ke ugqirha linyanzelise kwiwotshi of "chloramphenicol". Kodwa luni zixhobo akucetyiswa ukuba ikhethwe, zama ukuqonda.

iimpawu amayeza beziyobisi "Chloramphenicol"

Le zintsholongwane ukuba spectrum ezibanzi amanyathelo, ngenxa iipropati yalo nenqatha-enyibilikayo, ngokulula ingena iseli inwebu iintsholongwane kwaye idityaniswe into yokuba ribosomes bacteria. Isiphumo lweziphumo abanjalo isiphazamiso pepdidnyh iintambo ezenza neprotheyini yokuqaphela. Ngoko ke, kubonakala ukuba ubuncwane ichiza esebenzayo iye bactericidal kunye nesenzo bacteriostatic.

"Chloramphenicol" iyasebenza nxamnye Ngeentlobo ezininzi ezincinane ezo abanganyangekiyo tetracyclines, sulfonamides kunye penicillins. Kodwa elibangela yayintsholongwane eyosulela - sisifo sephepha Mycobacterium neenkowane - amayeza, ngelishwa, lungenasiphumo.

Ukumelana kule ndlela ezincinane uvela kancinane kakhulu. Ngenxa iimpawu ezifana kwakunye yetyhefu ephezulu ichiza asetyenziselwa ukunyanga izifo kakhulu ezosulelayo apho ube ngaphantsi zinetyhefu amachiza antibacterial angasebenzi.

Iimpawu zibonisa ukuba ukusetyenziswa kunye nefomu release

Ekubeni isixhobo isetyenziswa kwiindawo ezininzi amayeza, oosokhemisti ziye wanyamekela lula ukusetyenziswa kunye baphuhlisa iintlobo ezintathu ezingundoqo ichiza. Okokuqala - isisombululo utywala, nto leyo yenzelwe ukusetyenziswa yangaphandle. Oku kumiselwe ukuba unyango izilonda lwemithambo ukuba akukho ndiphilise ixesha elide, kwakunye zokutshiswa II kunye level III. Lidla Kucetyiswa ngeyeza ubovu kolusu, abile ingono koomama abalupheleyo.

Drug azipilisi bacetyiswa ukuba izigulane bathwaxwa zizigulo ezifana segazi, paratyphoid, yicesina, iBrucellosis, salmonellosis, tularemia, ithumba ebuchotsheni, inyumoniya. kweziyobisi Enye olusebenzayo iintlobo ezahlukeneyo Q fever, limfagranuleme inguinal, yersiniosis, psittacosis, usulelo iphecana biliary, peritonitis ubovu, chlamydia, usulelo yokubolisa ngenxeba, ehrlichiosis, ubovu otitis kunye nezifo womchamo imvelaphi yebhaktiriya.

Ifom yesithathu arhente - eyedrops. Zisetyenziswa xa befundisa lwamehlo ukulungiselela unyango kunye nothintelo lwezifo ezifana keratitis, conjunctivitis, blepharitis.

izixhobo kahle imithi

Le arhente amayeza, kwakunye nezinye iziyobisi, kodwa iimpawu ezintle amayeza lineqela side effects ezingenzeka ngethuba unyango.

Ukusetyenziswa kweziyobisi azipilisi kunokubangela i dysbacteriosis, ukuqunjelwa, ukugabha, isicaphucaphu, urhudo kunye kwinwebu pharynx kunye kwisisu ngomlomo. Phendula le ulwamkelo ithetha inkqubo kungenzeka hematopoietic, esizibonakalisa ngokohlobo thrombocytopenia, granulocytopenia, erythropenia, reticulocytopenia kunye leukopenia. Ngokuqhelekileyo, isigulane lisenokuba anemia aplastic okanye granulocytopenia. Xa i-luvo "Chloramphenicol" Amacwecwe abe neuritis peripheral, ukudideka, nemibono ezibonwayo kunye nezinto ezikhalayo, kunye nokuphazamiseka lengqondo al.

reactions Ezingalunganga ukuba ukusetyenziswa kweziyobisi kwifomu isisombululo kunokuba nokwaliwa, libonakaliswa njengoko amaqhakuvana ulusu okanye angioedema.

kusho analogue kwesakhiwo

Icandelo engundoqo esebenzayo ye ichiza chloramphenicol. Ngoko ke, le analogu noshowo "chloramphenicol" eziphambili - ichiza enegama elifanayo "Chloramphenicol". Iimpawu zibonisa ukuba ukusetyenziswa yalo twatse naleyo echazwe imiyalelo for "chloramphenicol" imiyalelo yosetyenziso.

Esi sixhobo iveliswa ngeendlela ezintathu eziphambili. Okokuqala - tablets kunye njengezingxobo eziqulathe 0.25 no-0.5 g mgaqo esebenzayo. Ifom yesibini yi-25% yokusithwa iliso, eyesithathu - umgubo elungiselelwe isisombululo ukuba ngenaliti.

Kubalulekile ukuqaphela ukuba, njengendlela "Chloramphenicol" analogs eziqulathe chloramphenicol na, antibiotics ebanzi-spectrum kwaye kufuneka banikwe ngqo ukuya kwagqirha. Kwiimeko of self-zolawulo eli qela iziyobisi kwandisa umngcipheko yeziphumo ebezingalindelekanga.

Drug "Levovinizol"

Enye Togu "chloramphenicol" zesakhiwo, leyo ngoku zingathengwa ekhemesti, eyaziwa phantsi igama lorhwebo "Levovinizol". Isiseko kwenani sisixhobo esisetyenziswayo chloramphenicol kunye excipients. iziyobisi Ifumaneka eluhlobo inkonxa, liniment, olungumgubo lokulungisa igqityiwe isisombululo kunye notywala nesisombululo.

Yabela isiyobisi esebenzayo lokosuleleka eluswini ezahlukeneyo bacteria okubangelwa amagciwane sifo. Ngaphezu koko, ngokufuthi oogqirha isicelo iyeza ukunyanga izigulana abasuleleke burns anzongonzongo ezingekhoyo, izilonda uxinzelelo, izilonda trophic, amanxeba ephilisa, amathumba, kwakhona abafazi medicament phindeke kunye ingono aqhekekileyo.

Ngokungafaniyo iziyobisi "Chloramphenicol" nucleoside mihla ngenxa isicelo mlonyeni, ingakumbi iziyobisi "Levovinizol" abe uluhlu emfutshane yeziphumo ebezingalindelekanga, kangangokuba ziyakwazi ukusetyenziswa ukunyanga abantwana ukususela ekuzalweni.

Ngokuphathelele Izimo, ngoko ke, kakhulu, hayi kangako. Iindlela zokuthintela abantu hypersensitivity ukuya amacandelo, inhibition of lomongo wethambo hematopoiesis, kwakunye nabo abaphethwe porphyria etsolo ngakanye, ukuswela glucose-6-phosphate dehydrogenase, insufficiency kwezintso okanye hepatic, ukhwekhwe, usulelo ezinzwaneni ye sangaphandle, nerhashalala.

Lithetha "sintomitsina"

Ukuzama ukuba alungise umbuzo wokuba yintoni na ichiza "Chloramphenicol" ntonye kunye analogue, qiniseka ukuba akhankanye medicament "sintomitsina". Eli yeza lidla emiselweyo kwizigulana eshe ezosulelekileyo 2-3rd elihlabayo, non-ephilisa izilonda trophic kunye nosulelo ezahlukeneyo inxeba.

Xa intliziyo ichiza esetyenziswayo kuthetha chloramphenicol. Njengokuba amacandelo kwanancedisayo ukudala idosi enye ifomu oosokhemisti basebenzisa zesiqhelo oyile imbewu kukaCastor, sorbic acid, amanzi nyulu, emulsifier № 1 kwaye carmellose sodium 70/450 "O".

Drug "Metronidazole"

Antiprotozoal kunye arhente antibacterial ezisetyenziswa kwiinkalo ezahlukeneyo yamayeza. Wamiselwa ngowe usulelo protozoan, izifo amalungu kunye namathambo, kwaye izigulo esiswini ngenxa umyalezo yebhaktiriya. Iveliswe iziyobisi esebenzayo ngeendlela idosi eziphambili ezine: ngokohlobo gel lobufazi, umxube iimela, suppositories kunye neepilisi.

Le Togu 'chloramphenicol' lurhudo kufuneka isetyenziswe kuphela kagqirha, oluya kucacisa indlela lokuqhubeka kwekhosi zonyango kunye balawule. Kungenjalo, umngcipheko reactions ebuhlungu umzimba kwandisa kakhulu. Kulo mzekelo, inkqubo luvo eliva ubunzima, kwaye izigulane ezikhala amahlaba, intloko, ukudinwa, sokulibala, isiyezi, ukuba nochuku, ukozela, Ataxia, ukudideka kunye nemibono. Ukongeza, ezizimeleyo ezithatha ichiza ukuze sibe sibi imeko yesigulane, uqinisa norhudo. Kusenokwenzeka ivele ukugabha, yimvakalelo ukoma emlonyeni, ilahleko epheleleyo namdla kunye nezinye ukuphazamiseka kwenkqubo yokwetyisa. Ngoko ke, njengokuba njengendlela "Chloramphenicol" imiyalelo zokusetyenziswa analogue icebisa ethatha kuphela kagqirha. Oku kuya kukunceda ukuba uphephe reactions kwicala ezingathandekiyo yaye ngokukhawuleza alungise le ngxaki ekhoyo.

Lithetha "ciprofloxacin"

Enye Togu of "chloramphenicol" - tablets "ciprofloxacin". Eli yeza onesiphumo antibacterial kwaye iyasebenza ulele zezifo ezininzi kwenkqubo genitourinary and Tract zesisu. Le umthamo ichiza kunye nelo lokuqhubeka kwekhosi unyango sibalwa ngamnye.

Eli yeza akukho analog noshowo lithetha "Chloramphenicol", kodwa iimpawu amayeza yale mithi ezimbini efana kakhulu. Ngapha koko, ukuze isetyenziselwe urhudo, okubangelwa iintsholongwane ezahlukeneyo izifo. Ngokumalunga contraindication ukusebenzisa-ntsholongwane "ciprofloxacin" ukuba eninzi kubo. Okokuqala, oko kuyathintelwa namayeza asetyenziselwa ukunyanga abantwana abafikisayo ayifikanga kweminyaka elishumi elinesihlanu. Okwesibini, ayikhuthazwa tu into yokuba ukusebenzisa iziyobisi abasetyhini ngexesha lokukhulelwa kunye zisanyisa. Isizathu sesokuba analogu of "chloramphenicol" ngummeli le quinolone ntsholongwane series, nto leyo angakhuli ithambo kunye intlala izihlunu, batshabalalisa ubume babo. Kwaye kuyingozi kakhulu iimvuthuluka ongekazalwa kwakunye ngomntwana, lwabo lweenkobe nokuncancisa.

Zintsholongwane "Amoxicillin"

Kwelinye ichiza antibacterial, neyathi yabonakala ngokugqibeleleyo ngokwayo unyango lwezifo wamathumbu abangela urhudo, yindlela "Amoxicillin". Njengoko amayeza "Chloramphenicol" analogue kuwo kufuneka kusetyenziswe kuphela phantsi ingcebiso zonyango. Ngapha koko, kukho inani elikhulu antibiotics zineziphumo ebezingalindelekanga. Ngoko ke, sabele isigulane-arhente antibacterial, ingcaphephe ubala kuphela umthamo ichiza, kodwa ukwazisa imithetho zokwamkelwa. Kananjalo kufuneka ukuba afake kunyango oluntsonkothileyo probiotics ezinokunceda ukunciphisa isiphumo esibi arhente antibacterial nokugcina flora eziqhelekileyo emathunjini.

Analogs "chloramphenicol" abantwana

Ukuba urhudo sele kuqalile kwi umntwana, self - hayi simse kule ngxaki. Ndingasazibaluli ke ukusetyenziswa ngokuzimeleyo arhente antibacterial yaye akunyanzelekanga ukuba. Into yokuqala omawuyenze ukuze ubone oyingcali uncedo. Ugqirha uya kuvanya kwiimvuthuluka, uya kubamba uthotho izifundo kwaye amisele ekhuselekileyo ukulungiselela unyango encinane nomonde. Kakade ke, ukuba sele uqinisekile ukuba unobangela urhudo yi igciwane, unyango ngaphandle antibiotics akunakwenzeka ukuba kunokwenzeka. Kodwa ke oku akuthethi ukuba ugqirha ukumisela amayeza "Chloramphenicol" nje. Analogs abantwana ezikhethiweyo ngokungqinelana nobudala beminyaka yomguli, ubungqongqo sifo, kwaye kananjalo ngokungqinelana iimpawu kwiimvuthuluka ngamnye (nokwaliwa, ukunyamezelana ukuba amayeza athile kunye namacandelo zabo, izifo ezinganyangekiyo, njalo njalo. D.).

Kaninzi Kwiimeko ezinjalo, ichiza eyenziweyo "nifuroxazide," nto leyo ebhekisela kwiqela nitrofurans. Ifumaneka njenge azipilisi kwaye ezingadibaniyo, le analogu "chloramphenicol." Amacwecwe zidla emiselweyo ukuba abantu abadala kunye nabantwana abafikelele kubudala bokuhamba isikolo, kodwa engamanzi fomu kuthetha ukuba unako imvuthuluka.

Zithathe amayeza zamehlo?

Ukuqwalasela iimpawu ichiza "Chloramphenicol" kunye analogue yayo, akufuneki silibale ukuba eli chiza antibacterial iza kwiintlobo ezahlukeneyo kwaye ingasetyenziswa kwiindawo ezininzi yamayeza. Umzekelo, wamehlo ezisetyenziswa kakhulu practice ophthalmologic ukuba unyango izifo ezibangelwa zizifo amagciwane. Iarhente nga kwenziwa ngabo izigulana conjunctivitis, blepharitis, keratitis, uveitis kunye nezinye izifo.

Noko ke, nangona ukusebenza ephakamileyo, ichiza ayikwazi Kucetyiswa ukuba bonke, njengoko uluhlu Izimo ukuba yokwamkela yayo inkulu ngokwaneleyo. Ngokungqinelana iinkcukacha eziqulathwe kule imiyalelo ukusetyenziswa, le medicament Akuvunyelwe ngokungqongqo ukuba abantwana abafikisayo abangaphantsi kweminyaka eli-18 kwabasetyhini ubudala, abakhulelweyo kunye nabongi. Izigulane abanezifo yenkqubo hematopoietic, insufficiency sezintso okanye hepatic kunye nezinye izigulo systemic kwaye awukwazi ukusebenzisa iziyobisi "Chloramphenicol" (eye amathontsi). Abo eziqulathe izithako ezikhuselekileyo kwiimeko ezinjalo - kuphela ukhetho oluchanekileyo zokusombulula le ngxaki. Kuxhomekeka kubudala yomguli kunye nobungozi besi sifo, ugqirha ingenza isindululo amachaphaza ezifana "sulfacetamide", "Okomistin", "Normaks", "Floksal" kunye nabanye.

Drug "Albucidum"

Njengoko "Chloramphenicol" drug (amathontsi), i-analogue "sulfacetamide" i medicament sinakho ukusebenza bacteriostatic. Le ichiza emiselweyo kwizigulana - nokuba ubudala -. Kuba nokuthintela kunye nokunyanga izifo iliso ezosulelayo ukudumba ezifana keratitis, conjunctivitis, blepharitis, njl Inye kuphela into eyimfuneko ukuze sinikele ingqalelo ekubeni ukuba unyango yabantwana isetyenziswa-20% beziyobisi iyapheliswa , kodwa amaqela ubudala nangaphezulu ibonisa-30%.

Xa siqwalasela iziphumo ebezingalindelekanga kunokwenzeka beziyobisi, oko kudla, ke kwenzeka kunqabile kakhulu yaye akazange afune unyango nomqondiso.

Into ekufuneka uyazi ichiza "Chloramphenicol" kunye analogs zayo?

Amayeza ezifanayo ngenye sakhelo lithetha "Chloramphenicol", hayi kangako. Kodwa nantsi amachiza ngempahla afanayo amayeza ingaphezulu ngokwaneleyo, yaye nguwuphi ukuba akhethe - kufuneka kumiselwa kuphela ngugqirha. Kuphela oyingcaphephe, oye wachitha Uxilongo aqingqa nobungozi besi sifo kunye umyalezo yayo, ukuze isindululo kumaziko ukwamkelwa nomonde "Chloramphenicol".

Analogs (utyatyazo, umzekelo) ngokohlobo amacwecwe nokumiswa, kakhulu, kufuneka athathwe kwi ngengcebiso kagqirha, emva ngokucacileyo inkqubo nomthamo. Oku kuza kucutha umngcipheko yeziphumo ebezingalindelekanga.