Isifo Berger likaThixo (IgA-nephropathy): ebangela, unyango

isifo sezintso kwenzeka kaninzi. Ezi ziquka izifo ezifana pielo- kunye glomerulonephritis. Ngaphandle kwezi, kukho ezinye izifo kwinkqubo womchamo. Enye yazo sisifo Berger kaThixo. Le ngezifo, kakhulu, libhekisela okungahambi rhoqo. Oku sifo e nama-20% amatyala izifo zezintso emadodeni. Le ukuhlukunyezwa asisebenzi kuphela iingxaki kwi-, njengoko uphuhliso indlela omzimba. Usola le ngezifo singaba uphawu engundoqo - hematuria gross.

isifo Berger kaThixo - ntoni na?

Esi sifo luhlobo glomerulonephritis ezigulo ezondeleyo. Ethelekiswa unesifo kunye ngobuwena nephrotic lwangoku, isifo Berger wehlabathi abane elungileyo. Nangona yokuba banesifo esemncinane (iminyaka 15-30), nto kunqabile iba insufficiency kakhulu sezintso. Ezibonisa ezingundoqo isifo - oku hematuria gross kuhlolwe kummandla empontshwa. Le ngezifo nako kwenzeke ebantwaneni. Xa amadoda livela izihlandlo 4 kaninzi ngaphezu abafazi. Njengazo zonke ezimbi, uphethwe i Classification International of Diseases (ICD). Nephropathy Berger N02 abe ikhowudi, elithetha "indawo hematuria oluzinzileyo yomhla nezolo."

Ezibangela isifo

Oyena nobangela uphambili esi sifo yinto yinkqubo esosulelayo. Kwiimeko ezininzi leengxaki sezintso emva izifo ezosulelayo amagciwane. Kwakhona, unobangela inokuba isifo ezinzwaneni. Iimpawu ngesiqhelo iintsuku ezimbalwa emva kokuba usulelo ingasekho kwisiqwenga zangentla ezihlasela zosulele ngokuphefumla (etsolo usulelo yokuphefumla lohlobo, umqala obuhlungu, pharyngitis). Unobangela ekhawulezileyo sifo ukuqokelelela izakhiwo ezigonyekileyo kweendonga sezintso nemithambo. Kwezinye iimeko, uqhagamshelwano ngezifo osindwa imbali amafa (kwiintsapho IgA-nephropathy). Ukongeza, esi sifo lu dityanisiwe yofuzo. Bucala le uphelelwe zilandelayo:

1. Emzimbeni.
2. Ukwehla nezifo.
3. iinkqubo Chronic wentsholongwane egazini kunye kwegciwane yomoya eliphezulu.

Indlela yesifo Berger bakhe

Le Pathogenesis kwesifo ezinxulumene yokulahlwa kwe izakhiwo omzimba kwi emithanjeni. Ngokwesiqhelo izixhobo kidney glomerular unoxanduva yokuhluza igazi. Siqulathe ezininzi iinqanawa nephrotic. Emva izinto zangaphambili ukusulelwa ukudumba - izakhiwo omzimba - emzimbeni kwaye ifakwe kwi-apparatus glomerular. Ngenxa yoko, ukuphuhlisa glomerulonephritis. iimpahla sezintso ayikwazi ukusebenza ngokuqhelekileyo ngenxa yokuba izakhiwo omzimba, kunye nama negazi kuphazanyiswa. Ukongeza, inkqubo yokukrala ebangela olwenzeka fluid (nokudumba parenchyma) kwaye kucutha permeability le ndizayo ongaphantsi. Ngenxa yoko, ukuphuhlisa hematuria olukhulu kunye ezincinane. Izizathu ezi nkqubo zihlala kumonakalo glomerular kunye kwii-ulwelo (igazi) ngokusebenzisa ndizayo ongaphantsi.

Zeziphi iimpawu zesifo kuvandlakanywa Berge?

Lo mfanekiso kwezonyango sifo Berger kaThixo kufana glomerulonephritis oyingozi. Kunjalo, kubalulekile ukuba umahluko phakathi kwezi zifo kunye. Unobangela glomerulonephritis into edla usulelo lwesikhumba. Kunye neendlela ezahlukeneyo zonyango ezi zifo. Iimpawu eziphambili Ig A-nephropathy zezi:

1. Hematuria. Amaninzi, lo umqondiso anyanzele izigulane ukuba zifune unyango. hematuria Gross kuthetha yimbonakalo igazi nomchamo. Oku kudla kunye mizwa ekhathazayo.
2. Microhematuria - oko luphawu leyo imperceptible ukuba abantu baza kuphela xa iisampuli ezizodwa.
3. Intlungu kummandla empontshwa. Amaninzi, ukuba ndiyaqaqanjelwa zibuthuntu indalo. Ngokungafaniyo nezinye iinkqubo ukudumba kwi izintso (pyelonephritis), ubuhlungu waphawula macala omabini.
4. Ubukho eliphezulu nokuphefumla usulelo phecana ngaphambili.
5. iqondo lobushushu emzimbeni Ukwandiswa.
6. ubuthathaka jikelele.
7. Proteinuria - imbonakalo iiprothini yokuchama. Ziphawuleka kwiimeko ezinqabileyo xa ikhosi Nedlac kwesi sifo.

Uxilongo Ig A-nephropathy

Isibaluli diagnostic sifo iphambili Berger kukuba ikhondo ezigulo ezondeleyo. Iimpawu yomguli zidla abachaphazelekayo malunga amaxesha 2-3 ngonyaka emva kokosuleleka. Kubalulekile ukuba uqaphele ukuba esi sifo kuba nabungozi. Nangona hematuria ngamaxesha wabonakalaliswa, kwezintso kuhlala eqhelekileyo. Ngokungafaniyo nezinye iinkqubo ukudumba (pielo-, glomerulonephritis), isifo CRF Berger xa kunqabile.

isifo Laboratory iquka pat OAM ezizodwa umchamo (nechyporenko, Zimnitsky). Kufuneka bachonge iiseli ezibomvu kunye iiseli ezimhlophe zegazi. Kuxhomekeka kolu khutsho nama- hematuria gross. Ngokubanzi, uhlalutyo leeprothini umchamo kunokuba khona. Ukukhangela ukuba ngaba kukho lunyhasho umsebenzi kwezintso, isigulane kufuneka unikele ngegazi ukusuka apho iphuma khona ngamachiza ezinto eziphilayo. Kule analysis, kubalulekile ukwazi umgangatho creatinine, oko kuyinto eqhelekileyo xa sifo Berger. Ukubeka uxilongo lokugqibela, uphononongo olwenziwe ubukho Ig A egazini. Kwiimeko ezinqabe a biopsy zezintso, apho izakhiwo wokugonyeka ezifumaneka isixhobo nemithambo. Ultrasound kwakhona lwenziwa ngenxa uxilongo umahluko.

Ngumzimba ukudumba sezintso: unyango

Nangona ikhondo elihle isifo ngexesha unyango iphinde iyafuneka. Kuyimfuneko kuphela ukuba lula iimpawu zesifo, kodwa ngenjongo ekuthinteleni iingxaki nokulondoloza umsebenzi kwezintso. Unyango iqala nge kulungiswe nakujoliso olutsha usulelo. Kwiimeko ezininzi oku Imithi (iziyobisi "amoxicillin", "Cefazolin") kunye arhente antiviral (imithi "Viferon", "Genferon"). Ukongeza, ukunciphisa ukudumba kwi NSAIDs izixhobo kidney glomerular olufunekayo. iziyobisi "Kanefron" bavame kusetyenziswa, "ibuprofen". Xa isifo sezintso na amayeza esebenzayo ezisekelwe imifuno. Utyumbe iti ezizodwa kunye infusions (knotweed, namaqhina ezinde, bearberry).

Ukuba isifo nzima ukunyanga, abe sisifo rhoqo okanye iingxaki, ngoko tirhisa unyango hormone. Ngokuqhelekileyo ukumisela ichiza "Prednisolone", kunye arhente osebenzayo. Kwezinye iimeko, kwanonyango antiplatelet, yindlela ukuze kuphuculwe ukuhamba kwegazi (iziyobisi "Kurantil").

Uthintelo isifo Berger bakhe

Kufuneka kukhunjulwe ukuba isifo Berger isixelela ukuba ezimbi ezigulo ezondeleyo. Ngoko ke, ukuze uphephe exacerbations, amanyathelo othintelo kufuneka kwenziwe. ixesha Kubalulekile ukuba ukuphilisa i nakujoliso olutsha losulelo (tonsils, sinusitis), kufuneka phantsi emzimbeni. Kwakhona, izigulane kufuneka ukuba izifundo amayeza ngamaxesha esintu, ukuxhasa amajoni omzimba.