"I-Miniziston": ukuphononongwa kunye nezifana

Kumntu, ukukhulelwa kungaba ngumcimbi ovuyayo kwaye ulinde ixesha elide, kunye nezinye izibini - intshabalalo epheleleyo. Ngoko ke, umfazi ongakalungiseleli ukuba ngumama, kufuneka akhuselwe ekukhulelweni okungafunekiyo. Iyeza zanamhlanje zinika ukhetho oluninzi lwezo zonke iintlobo zokukhulelwa. Enye yezona ndlela zisebenza ngolu hlobo "Miniziston". Iingxelo zabasetyhini malunga neziyobisi zinokuva

Ukukhutshwa kwefom, ukubunjwa kunye nokupakishwa kwamacwecwe

"I-Miniziston" yindlela yokukhulelwa yodwa ngokulawula komlomo. Kuveliswe ngendlela yeepilisi kwi-pinki. Izithako ezisebenzayo ekubunjweni yi-ethinyl estradiol kunye ne-levonorgestrel. Izixhobo ezincedisayo:

• Isitashi sommbiwa;
• Lactose monohydrate;
• Povidone;
• I-Magnesium stearate;
• I-calcium carbonate;
• Stearose;
• Idayi e-Red iron dioxide;
• I-Wax intaba ye-glycolic.

Amacwecwe aphakathi kwe-blister, 21 nganye. Kwiphakheji enye ye-pharmacy inokufumaneka kwiiplati enye ukuya kwethathu kunye neyeza.

I-Pharmacological action

Ukukhulelwa komzimba okuhlangeneyo kunye nokulawulwa komlomo. Isiphumo sokukhulelwa kwe-"Miniziston 20" sisekelwe kwisenzo esiyinkimbinkimbi yimiba eyahlukeneyo, eyona nto ibaluleke kakhulu kukuxinzelelo kwe-ovulation kunye noshintsho kwi-viscosity ye-mucus yomlomo wesibeleko.

Kwakhona indlela yokukhulelwa kwanamhlanje iya kunceda ukuphelisa ezinye iintsholongwane zenkqubo yesetyhini yokuzala:

• Ukuqhelanisa umjikelezo wesini.
• Ukunciphisa intlungu ngexesha leentsuku ezibalulekileyo.
• Ukuhamba kokuya esikhathini akusiyo ininzi kakhulu ekuncedeni ukunciphisa umngcipheko we-anemia.

Namhlanje ininzi ethandwa kakhulu kwaye ithandwa phakathi kwabantwana bezilwanyana kunye nezigulane zabo yiyeza "Miniziston". Ukuphonononga malunga neziyobisi zilungile, njengoko kungalimazi umzimba kwaye kufumaneka kwisicelo.

Levonorgestrel

Emva kokungcinywa, i-levonorgestrel yezinto ezinobungozi ngexesha elifutshane kwaye lixakeke ngokupheleleyo. Kwi-serum, isixa esiphezulu sesilwanyana sifinyelelwa kwiyure. Apha, i-levonorgestrel idibanisa ne-albumin kunye ne- globulin, ebopha i-hormone yesondo.

Ngokutya kwansuku zonke, loo nto iqokelela kwisigaba sesibini sokuphuma kwaye ifinyelele kwisithuba sayo esiphezulu kwisithuba se-4. I-Pharmacokinetics ixhomekeke ngqo kwi-hormone yegazi eplasma. Ngenxa yokuba kukho i-ethinyl estradiol ekubunjweni, umxholo we-hormone ukhuphuka malunga nama-70% ngokubanjwa kwe-Miniziston 20. Amazwi oogqirha kwiiyeza aya kunceda isigulane senze ukhetho olufanelekileyo lweepilisi zokukhusela ukukhusela ukukhulelwa okungalindelekanga.

I-Levonogestrol yenziwe ingatshintshi. Iimetabolites zakhe ngaphakathi komhla ziya kumchamo. Ukugxininiswa kwesilwanyana kwiplasma kuncitshiswe ngamanyathelo amabini. Ixesha lokuqala lithatha isigqibo seyure, kwaye okwesibini kuthatha iiyure ezingama-20.

Ethinylestradiol

Xa utywala, ukuxhamla ngokukhawuleza kwenzeka. Emva kweeyure ezingama-2, ukuxinwa okuphezulu kwigazi kufinyelelwe. Esesibindi, i-substance i-metabolized. I-Ethinylestradiol i-100% ifakwe kwi-albumin. Egazini, ukuxinwa kwe-arhente kuncitshiswe kumanyathelo amabini. Ixesha lokuqala lithatha malunga neyure, iiyure eziyi-10 okanye ezingama-20. Ukupheliswa ngokupheleleyo kumzimba. Iimetaboliti ziphuma ngaphandle kweeyure ezingama-24.

Iinkcazo kunye nokuchasene

Ukulungiselelwa "i-Miniziston" kuboniswe ukukhusela ukukhulelwa. Iimpendulo zeengcali zibonisa ukuba iyeza linemibuzo engqinelanayo. Musa ukunika umyalelo wokukhulelwa kwezi zilandelayo:

• Ukuba isiguli sinesifo esichukumisayo okanye esingapheliyo okanye sisifo esiyingozi.
• Xa kukho ukuthambekela kwe-thrombosis ku-anamnesis okanye ngexesha elithile. Ngokomzekelo, ukuphazamiseka kwexesha elingasemva kwe-cerebral circulation.
• Ubuninzi besifo sikashukela, obunzima ngokuphulwa kwenkqubo ye-cardiovascular system.
• Ukuxhamla kwezitho zomzimba okanye izilwanyana ezincinci ezixhomekeke kwi-hormone.
• Ukuphuma kwamanzi ngesisu.
• Iziqhamo ezivelisayo.
• Ukuncelisa.
• Izibilini zesifo seBenign okanye esibi.
• Ukunyanzeliswa kwamanzi kwiinkalo zesilwanyana.

Isistim

Thatha amayeza ngokuqhubekayo kwindlela eboniswe kwipakethe. Iipilisi kufuneka zihlanjwe ngaphantsi kwamanzi amaninzi. Ngaphambi kokusetyenziswa, imfundo yokulungiselela i-"Miniziston" kufuneka ifundwe. Ingxelo evela kwiingcali ibonisa ukuba i-regimen ichazwe ngethuba lomjikelezo wesini.

Emva kokukhipha isisu kwi-trimester yokuqala yokukhulelwa, kufuneka uqale ukuthatha iipilisi ngokukhawuleza. Ukukhuselwa okongeziweyo akukho mfuneko. Emva kokusebenza kunye nokukhipha isisu ekukhulelweni kwexesha elide, kufuneka uqale ukuthatha iyeza ngomhla we-21 okanye ngowama-28. Ukuba ulahlekelwe ixesha elimiselweyo lokungeniswa, kufuneka uphuze ipilisi ngokukhawuleza, isilinganisi esilandelayo kufuneka sithathwe kwishedyuli rhoqo. Ukuba usuphelile malunga nomhla, ukuphumelela kokukhulelwa komzimba akuhla.

Ukugqithisa

Akukho naluphi ulwazi malunga nokugqithisa kweziyobisi. Kwiimeko eziqhelekileyo, kunokuxhatshazwa kancinci kunokwenzeka, okubonakaliswa yincwadana kunye nokuhlanza. Xa ezi zibonakaliso zibonakaliswa, unyango lwe-detoxification luyenziwa kwaye isisu siyahlanjwa.

Ukusebenzisana namanye amachiza

Ngolawulo oluhlanganyelweyo lweziyobisi "Miniziston" kunye neziyobisi ezenza i-enzymes microsomal yesibindi, ukukhutshwa kwe-ethinyl estradiol kunye ne-levonorgesterol kunokunyuka, okuya kwenza ukuba ukukhulelwa komzimba kungasebenzi kwaye kungaholela ekuphumeni kwegazi. Kukho nenani leziyobisi ezingenakuthathwa kunye neyeza leMizziston. Ezi ziquka:

• "Oxcarbazepine";
• "Topiramat";
• Felbamate;
• Ampicillin;
• "Tetracycline";
• Rifampicin.

Ukukhulelwa kunye nexesha lokuncelisa

Ukuba ukukhulelwa kufunyanwe xa uthatha isiza, ikhutshwe ngokukhawuleza kwaye kamva ayikwamukelwa. Ngokwezibalo, akukho mntwana walimala xa ethatha isithintelo sokukhulelwa kwinqanaba lokuqala lokukhulelwa, xa lingakabonakali.

Akukhuthazwa ukusela i-Miniziston ngexesha lokuncelisa. Izimvo zesigulane zibonisa ukuba le mpilisi inciphisa inani lemfuyo kwaye liguqula ukubunjwa kwalo. Nangona inobungozi kwimpilo yesilwanyana esandula kuzalwa ayibangeli.

Imiphumo emibi

Ngokwenene, isilwanyana sinyamezeleke, kodwa kwiimeko ezizodwa, ezi zilandelayo ziyakwenzeka:

• I sihlunu;
• Ukuvutha;
• Utshintsho kwi-secretal vaginal;
• Utshintsho kwiintlanzi zamathambo: ukuvuvukala, ukunyamezela, ukuvuvukala, ukukhupha kwiimbumba;
• Ukwanda komzimba; Ukunciphisa umnqweno wesini;
• Ubuhlungu entloko, i-migraine;
• Ukuguqulwa kwamanzi;
• Edema;
• Chloasma.

Imiyalelo ekhethekileyo

Ugqirha kuphela onokumisela iipilisi "Miniziston". Uphononongo lubonisa ukuba ngaphandle kweengcebiso zengcali, abaninzi abafazi bathabatha iyeza ngokungalunganga.

Isigulane sifanele sixelelwe ukuba kunye nokuphuhliswa kweempawu ze-thrombosis okanye i-thrombosis yenyango, kufuneka ugqirha kuthethwe.

Ukwamukelwa kweemali ezikhuselekileyo zesibindi kunye nesifo sezintso, kunye ne-jaundice. Gcina iyeza kwindawo epholileyo kunye emnyama, kude nabantwana abancinci. Ngaphambi kokuba uqale ukuyithatha, funda ngokucophelela imiyalelo kunye nomhla wokugqitywa kwiphakheji.

Ukuba ukukhulelwa komzimba akufumaneki kwikhemistri, ingcali iza kukwazi ukuphakamisa i-analogue esemgangathweni. Abafakiweyo abathandwa kakhulu baya kuchazwa ngezantsi.

"Microgonon"

Ukukhulelwa kweMonophasic yokulawulwa komlomo. Kuveliswe ngendlela ye-dragée. Izinto eziphambili kwipilisi yi-ethinyl estradiol kunye ne-levonorgestrel.

Umlomo womnxeba womzimba owenzela i-contraoptive "Microgonon" unesisindo esifanayo njenge-Miniziston. Uphononongo malunga nalezi zonyango zikhulu kakhulu. Abazilimazi umzimba kwaye bathathwa kuphela kanye ngosuku. Amayeza achazwa ngala maziko:

• Ukucinezelwa kwe-ovulation kwinqanaba le-hypothalamic-pituitary;
• Utshintsho kwi-viscosity ye-mucus yomlomo wesibeleko, ngenxa yalokho i-spermatozoa ayikwazi ukungenelela kwisigxina se-uterine;
• Sitshintsha kwi-endometrium, engavumelekanga iqanda elichumayo ukuba lizinze kwisibeleko;
• Ukuqhelaniswa kwemisitho, ukungabikho ubuhlungu kunye nokunciphisa ukukhulelwa kwamanzi.

Iinkcazo kunye nokuchasene

Isilwayo sichazwe njengendlela yokukhulelwa. Kukho ukungqinelana kokumkelwa kwayo:

• Isifo sikashukela;
• Iintlobo ezihlukahlukeneyo zendalo kunye nobuhlungu obungapheliyo;
• Iintloko zentloko;
• Pancreatitis;
• Ukungafezeki kwe-Hepatic kunye ne-renal nezinye iimeko.

Ngaphambi kokuqala kwonyango kufuneka kufundwe, njengoko kwimeko yamacwecwe "Miniziston", umyalelo. Uphononongo lubonisa ukuba iziphumo eziphambili zihlala ziziphumo zokusetyenziswa kakubi kweziyobisi.

Isistim

Ukupakisha kubonisa ukulandelelana kweengqungquthela. Thatha enye ipilisi ngosuku. Ukusela imithi kuyimfuneko iintsuku ezingama-21, inqanaba elilandelayo liqala emva kwekhefu leentsuku ezi-7. Ngeli xesha, ukuphuma kwindoda kuphuma.

Imiphumo emibi:

• Spotting spotting;
• I sihlunu;
• Ukuvutha;
• Ukuzuza ubunzima;
• Ukukhathazeka nokuvuvukala kweengcambu zeemfesane;
• Ukuguqulwa kwamanzi.

Kwi-pharmacy, iyeza linikezelwa kumyalelo wecawa. Awukwazi ukumisela isilungiso sesibindi esinamandla nesifo seengtso. Gcina iindawo ezinqamlekileyo kubantwana, kwindawo epholile kunye eyomileyo.

Oralcon

Esi sidakamizwa singaphinda sithathe iipilisi "Miniziston." Uhlolo lweengcali lubonisa ukuba iziyobisi azifani ngokubunjwa kwaye zinomphumo ofanayo kumzimba wesetyhini. I-Oralcon yindlela yokukhulelwa ngomlomo. Iveliswe ngendlela yamacwecwe amhlophe. Iinqununu eziphambili zeliyobisi yi-levonorgestrel kunye ne-ethinyl estradiol.

Iyeza linezi ndawo ezilandelayo:

• Ugxininisa i-ovulation.
• Ukwandisa i-viscosity ye-mucus yomlomo wesibeleko, okuvimbela ukungena kwesidoda kwisisu.
• Ukumisela umjikelo.
• Ukuhamba kweentsuku eziphambili ngaphandle kokunyuka kwegazi kunye nentlungu.

Iinkcazo kunye nokuchasene

Isilwayo siboniswe ukukhusela ukukhulelwa okungafunekiyo. Ukwacelwa ukuba kube neengxaki ze-hormone ezixhomekeke kwimijikelezo yenyanga. I-arhente inamanyathelo afanayo kunye nokulungiselela iMizziston. Ubungqina boogqirha bubungqina bokuba phakathi kwezigulane amayeza ayenziwa ngokufanayo.

Musa ukumisela izilwanyana "Oralcon" ngezi zifo zilandelayo:

• Iimpawu ze-thrombosis ebomvu okanye ebomvu;
• Isifo sikashukela;
• Izifo ze-Vascular;
• Ukuguguzwa komnxeba kunye nokuphazamiseka kwesibindi;
• Iintsholongwane zeeurolotiki;
• Ukukhulelwa;
• Ukuncelisa;
• Ukutyhelwa kwemvelaphi engaziwayo;
• Ukunyanzeliswa kweziyobisi kwiziyobisi.

"I-Oralcon" ineengqinano ezifanayo zokungeniswa, kunye namacwecwe "i-Miniziston 20".

Impendulo ibonisa ukuba ukukhulelwa komlomo kungaba ngummeli othembekileyo ekukhulelweni okungafunekiyo. I-Miniziston, kunye neengalo zalo (Oralcon, Microgonon, Antevin, Ovidon, Tri-Regol) zisebenza kakuhle. Kodwa ukuze uzikhusele kwizifo ezithathelwana ngesondo, ukusebenzisa iipilisi akuyi kuphumelela.